Glucoraphanin potassium salt, Sulforaphane bioprecursor (ab143626)

Overview

  • Product name

    Glucoraphanin potassium salt, Sulforaphane bioprecursor
  • Description

    Sulforaphane bioprecursor. Cytochrome P450 and phase II conjugation activity modulator.
  • Biological description

    Sulforaphane (ab141969, ab141971) bioprecursor. Cytochrome P450 and phase II conjugation activity modulator. Glucoraphenin (ab143627) analog. Shows chemopreventive and anti-inflammatory effects in vivo. Orally active.
  • Purity

    > 98%
  • CAS Number

    21414-41-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    [(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl] (1E)-(5R)-methylsulfinyl-N-sulfooxypentanimidothioate potassium salt
  • Molecular weight

    475.60
  • Molecular formula

    C12H22KNO10S3
  • Storage instructions

    Store at +4°C. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    [O-][S@@+](C)CCCCC(=N\OS(=O)(=O)O[K])/S[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Galuppo M  et al. Anti-inflammatory and anti-apoptotic effects of (RS)-glucoraphanin bioactivated with myrosinase in murine sub-acute and acute MPTP-induced Parkinson's disease. Bioorg Med Chem 21:5532-47 (2013). Read more (PubMed: 23810671) »
  • Ares AM  et al. Extraction, chemical characterization and biological activity determination of broccoli health promoting compounds. J Chromatogr A 1313:78-95 (2013). Read more (PubMed: 23899380) »
  • Perocco P  et al. Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and increases free radical generation in rat liver. Mutat Res 595:125-36 (2006). Read more (PubMed: 16442570) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab143626.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up