Glucosamine sulfate, Postranslational modification regulator (ab143629)

Overview

  • Product name

    Glucosamine sulfate, Postranslational modification regulator
  • Description

    Postranslational modification regulator
  • Biological description

    Postranslational modification regulator. Inhibits N-glycosylation of certain proteins. Regulates TGF-β signaling. Downregulates HIF-1. Suppresses 5-HT-induced nociceptive responses. Shows analgesic effects in vivo. Orally active.
  • Purity

    > 96%
  • CAS Number

    29031-19-4
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    Glucosamine hemisulfate potassium chloride
  • Molecular weight

    302.76
  • Molecular formula

    C6H15NO9S.0.5H2SO4.KCl
  • PubChem identifier

    115046
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O)[C@@H]1N.Cl[K].Cl[K].O=S(=O)(O)O.OC[C@H]1O[C@@H](O)[C@H](N)[C@@H](O)[C@@H]1O
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Moye ZD  et al. Uptake and Metabolism of N-Acetylglucosamine and Glucosamine by Streptococcus mutans. Appl Environ Microbiol : (2014). Read more (PubMed: 24928869) »
  • Chesnokov V  et al. Anti-cancer activity of glucosamine through inhibition of N-linked glycosylation. Cancer Cell Int 14:45 (2014). Read more (PubMed: 24932134) »
  • Hwang JS  et al. Basal transcription is regulated by lipopolysaccharide and glucosamine via the regulation of DNA binding of RNA polymerase II in RAW264.7 cells. Life Sci : (2014). Read more (PubMed: 24968300) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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