Anti-GLUT5 antibody (ab41533)
Key features and details
- Rabbit polyclonal to GLUT5
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GLUT5 antibody
See all GLUT5 primary antibodies -
Description
Rabbit polyclonal to GLUT5 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to GLUT5 (C terminal).
(Peptide available asab171722) -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
Isolated on antigen-sepharose affinity column. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab41533 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000. Predicted molecular weight: 55 kDa.
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Notes |
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WB
1/1000. Predicted molecular weight: 55 kDa. |
Target
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Function
Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter. -
Tissue specificity
Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue. -
Sequence similarities
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 6518 Human
- Omim: 138230 Human
- SwissProt: P22732 Human
- Unigene: 530003 Human
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Alternative names
- Facilitated glucose transporter member 5 antibody
- Fructose transporter antibody
- Glucose transporte, kidney antibody
see all
Images
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Anti-GLUT5 antibody (ab41533) at 1 µg/ml + Human small intestine tissue lysate - total protein (ab29276) at 10 µg
Secondary
Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 55 kDa
Observed band size: 55 kDa
Additional bands at: 25 kDa, 71 kDa. We are unsure as to the identity of these extra bands.
Exposure time: 20 minutes
Datasheets and documents
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Datasheet download
References (4)
ab41533 has been referenced in 4 publications.
- Jones N et al. Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation. Nat Commun 12:1209 (2021). PubMed: 33619282
- Zhang X et al. Reactive oxygen species-induced TXNIP drives fructose-mediated hepatic inflammation and lipid accumulation through NLRP3 inflammasome activation. Antioxid Redox Signal 22:848-70 (2015). PubMed: 25602171
- Gonzalo-Gobernado R et al. Neuroprotective activity of peripherally administered liver growth factor in a rat model of Parkinson's disease. PLoS One 8:e67771 (2013). WB . PubMed: 23861803
- Mellor KM et al. Fructose modulates cardiomyocyte excitation-contraction coupling and Ca²? handling in vitro. PLoS One 6:e25204 (2011). PubMed: 21980397