Anti-Glucose Transporter GLUT1 antibody [EPR3915] (ab115730)

Rabbit recombinant monoclonal Glucose Transporter GLUT1 antibody [EPR3915]. Validated in WB, IHC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Human. Cited in 41 publication(s).

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ab115730 has been referenced in 43 publications.

  • Martinez CA  et al. Obstructive Sleep Apnea Activates HIF-1 in a Hypoxia Dose-Dependent Manner in HCT116 Colorectal Carcinoma Cells. Int J Mol Sci 20:N/A (2019). PubMed: 30669593
  • Oliveira H  et al. GLUT1 and GLUT3 involvement in anthocyanin gastric transport- Nanobased targeted approach. Sci Rep 9:789 (2019). PubMed: 30692585
  • Qu S  et al. Aneustat (OMN54) has aerobic glycolysis-inhibitory activity and also immunomodulatory activity as indicated by a first-generation PDX prostate cancer model. Int J Cancer 143:419-429 (2018). PubMed: 29441566
  • Romero-Cordoba SL  et al. Loss of function of miR-342-3p results in MCT1 over-expression and contributes to oncogenic metabolic reprogramming in triple negative breast cancer. Sci Rep 8:12252 (2018). PubMed: 30115973
  • Yang Q  et al. PRKAA1/AMPKa1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis. Nat Commun 9:4667 (2018). PubMed: 30405100
  • Håversen L  et al. Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice. Sci Rep 8:16973 (2018). PubMed: 30451917
  • Chen YH  et al. Asymmetric PI3K Activity in Lymphocytes Organized by a PI3K-Mediated Polarity Pathway. Cell Rep 22:860-868 (2018). ICC/IF . PubMed: 29420173
  • Wang T  et al. Glycolysis is essential for chemoresistance induced by transient receptor potential channel C5 in colorectal cancer. BMC Cancer 18:207 (2018). PubMed: 29463225
  • Ioja S  et al. Nocturnal Hypoxia Improves Glucose Disposal, Decreases Mitochondrial Efficiency, and Increases Reactive Oxygen Species in the Muscle and Liver of C57BL/6J Mice Independent of Weight Change. Oxid Med Cell Longev 2018:9649608 (2018). PubMed: 29507654
  • Li Y  et al. Large Intergenic Non-coding RNA-RoR Inhibits Aerobic Glycolysis of Glioblastoma Cells via Akt Pathway. J Cancer 9:880-889 (2018). PubMed: 29581766
  • Wang F  et al. The Warburg effect in human pancreatic cancer cells triggers cachexia in athymic mice carrying the cancer cells. BMC Cancer 18:360 (2018). PubMed: 29609556
  • Chen Z  et al. MiR-3662 suppresses hepatocellular carcinoma growth through inhibition of HIF-1a-mediated Warburg effect. Cell Death Dis 9:549 (2018). PubMed: 29748591
  • Deng Y  et al. mTOR-mediated glycolysis contributes to the enhanced suppressive function of murine tumor-infiltrating monocytic myeloid-derived suppressor cells. Cancer Immunol Immunother 67:1355-1364 (2018). PubMed: 29968153
  • Femenía T  et al. Disrupted Neuroglial Metabolic Coupling after Peripheral Surgery. J Neurosci 38:452-464 (2018). PubMed: 29175959
  • Jin W  et al. Long non-coding RNA TUC338 is functionally involved in sorafenib-sensitized hepatocarcinoma cells by targeting RASAL1. Oncol Rep 37:273-280 (2017). PubMed: 27878301
  • Wang T  et al. Elevated expression of TrpC5 and GLUT1 is associated with chemoresistance in colorectal cancer. Oncol Rep 37:1059-1065 (2017). PubMed: 28000878
  • Li G  et al. Deletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality. Cell Death Dis 8:e2811 (2017). PubMed: 28542142
  • Kvainickas A  et al. Retromer- and WASH-dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50. J Cell Sci 130:382-395 (2017). PubMed: 27909246
  • Nguyen A  et al. Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1a axis inhibition. Oncotarget 8:71597-71617 (2017). PubMed: 29069732
  • Kunisada Y  et al. Attenuation of CD4+CD25+ Regulatory T Cells in the Tumor Microenvironment by Metformin, a Type 2 Diabetes Drug. EBioMedicine 25:154-164 (2017). Flow Cyt ; Mouse . PubMed: 29066174
  • Jones N  et al. Metabolic Adaptation of Human CD4+and CD8+T-Cells to T-Cell Receptor-Mediated Stimulation. Front Immunol 8:1516 (2017). PubMed: 29170670
  • Hu L  et al. Emodin and rhein decrease levels of hypoxia-inducible factor-1a in human pancreatic cancer cells and attenuate cancer cachexia in athymic mice carrying these cells. Oncotarget 8:88008-88020 (2017). PubMed: 29152137
  • Shi W  et al. N-Myc downstream-regulated gene 2 restrains glycolysis and glutaminolysis in clear cell renal cell carcinoma. Oncol Lett 14:6881-6887 (2017). PubMed: 29163707
  • Kratchmarov R  et al. IRF4 Couples Anabolic Metabolism to Th1 Cell Fate Determination. Immunohorizons 1:156-161 (2017). Flow Cyt ; Mouse . PubMed: 28944344
  • Kanow MA  et al. Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye. Elife 6:N/A (2017). PubMed: 28901286
  • Siska PJ  et al. Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma. JCI Insight 2:N/A (2017). Flow Cyt ; Human . PubMed: 28614802
  • Uri A  et al. Protection of Mice from Acute Graft-versus-Host Disease Requires CD28 Co-stimulation on Donor CD4(+) Foxp3(+) Regulatory T Cells. Front Immunol 8:721 (2017). Flow Cyt ; Mouse . PubMed: 28690612
  • Ung PM  et al. Inhibitor Discovery for the Human GLUT1 from Homology Modeling and Virtual Screening. ACS Chem Biol 11:1908-16 (2016). PubMed: 27128978
  • Xu Y  et al. Glycolysis determines dichotomous regulation of T cell subsets in hypoxia. J Clin Invest 126:2678-88 (2016). PubMed: 27294526
  • Lu K  et al. Expression and clinical significance of glucose transporter-1 in pancreatic cancer. Oncol Lett 12:243-249 (2016). IHC-P ; Human . PubMed: 27347132
  • McMillan KJ  et al. Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins. J Cell Biol 214:389-99 (2016). PubMed: 27528657
  • Khanom R  et al. Keratin 17 Is Induced in Oral Cancer and Facilitates Tumor Growth. PLoS One 11:e0161163 (2016). PubMed: 27512993
  • Tong D  et al. The HIF/PHF8/AR axis promotes prostate cancer progression. Oncogenesis 5:e283 (2016). Human . PubMed: 27991916
  • Chen K  et al. Regulation of glucose metabolism by p62/SQSTM1 through HIF1a. J Cell Sci 129:817-30 (2016). PubMed: 26743088
  • Zhu Y  et al. An Oncogenic Virus Promotes Cell Survival and Cellular Transformation by Suppressing Glycolysis. PLoS Pathog 12:e1005648 (2016). WB, IHC-P ; Rat . PubMed: 27187079
  • Maekawa Y  et al. Notch controls the survival of memory CD4+ T cells by regulating glucose uptake. Nat Med 21:55-61 (2015). PubMed: 25501905
  • Shi S  et al. Metabolic tumor burden is associated with major oncogenomic alterations and serum tumor markers in patients with resected pancreatic cancer. Cancer Lett 360:227-33 (2015). WB ; Human . PubMed: 25687883
  • Qin W  et al. Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells. Oncotarget 6:39839-54 (2015). WB ; Human . PubMed: 26497999
  • Boyer-Di Ponio J  et al. Instruction of circulating endothelial progenitors in vitro towards specialized blood-brain barrier and arterial phenotypes. PLoS One 9:e84179 (2014). WB . PubMed: 24392113
  • Saucillo DC  et al. Leptin metabolically licenses T cells for activation to link nutrition and immunity. J Immunol 192:136-44 (2014). PubMed: 24273001
  • Caro-Maldonado A  et al. Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. J Immunol 192:3626-36 (2014). PubMed: 24616478
  • Cao Y  et al. Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells. PLoS One 9:e104104 (2014). WB ; Mouse . PubMed: 25090630
  • Foster R  et al. Multiple Metabolic Alterations Exist in Mutant PI3K Cancers, but Only Glucose Is Essential as a Nutrient Source. PLoS One 7:e45061 (2012). WB . PubMed: 23028762


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