Recombinant Anti-Glucose Transporter GLUT1 antibody [EPR3915] (ab115730)

Rabbit recombinant monoclonal Glucose Transporter GLUT1 antibody [EPR3915]. Validated in WB, IHC, Flow Cyt, ICC/IF and tested in Mouse, Rat, Human. Cited in 41 publication(s).

Publishing research using ab115730? Please let us know so that we can cite the reference in this datasheet.

ab115730 has been referenced in 55 publications.

  • Martinez CA  et al. Obstructive Sleep Apnea Activates HIF-1 in a Hypoxia Dose-Dependent Manner in HCT116 Colorectal Carcinoma Cells. Int J Mol Sci 20:N/A (2019). PubMed: 30669593
  • Oliveira H  et al. GLUT1 and GLUT3 involvement in anthocyanin gastric transport- Nanobased targeted approach. Sci Rep 9:789 (2019). PubMed: 30692585
  • Houghton MJ  et al. Gut microbiome catabolites as novel modulators of muscle cell glucose metabolism. FASEB J 33:1887-1898 (2019). PubMed: 30183376
  • Fujii N  et al. Impact of aging and caloric restriction on fibroblast growth factor 21 signaling in rat white adipose tissue. Exp Gerontol 118:55-64 (2019). PubMed: 30620889
  • Chen J  et al. SIRT1 promotes GLUT1 expression and bladder cancer progression via regulation of glucose uptake. Hum Cell 32:193-201 (2019). PubMed: 30868406
  • Najjar YG  et al. Tumor cell oxidative metabolism as a barrier to PD-1 blockade immunotherapy in melanoma. JCI Insight 4:N/A (2019). PubMed: 30721155
  • Xu L  et al. SIRT3 elicited an anti-Warburg effect through HIF1a/PDK1/PDHA1 to inhibit cholangiocarcinoma tumorigenesis. Cancer Med 8:2380-2391 (2019). PubMed: 30993888
  • Pyaram K  et al. Keap1-Nrf2 System Plays an Important Role in Invariant Natural Killer T Cell Development and Homeostasis. Cell Rep 27:699-707.e4 (2019). PubMed: 30995469
  • Ye G  et al. Lamc1 promotes the Warburg effect in hepatocellular carcinoma cells by regulating PKM2 expression through AKT pathway. Cancer Biol Ther 20:711-719 (2019). PubMed: 30755064
  • Qu S  et al. Aneustat (OMN54) has aerobic glycolysis-inhibitory activity and also immunomodulatory activity as indicated by a first-generation PDX prostate cancer model. Int J Cancer 143:419-429 (2018). PubMed: 29441566
  • Romero-Cordoba SL  et al. Loss of function of miR-342-3p results in MCT1 over-expression and contributes to oncogenic metabolic reprogramming in triple negative breast cancer. Sci Rep 8:12252 (2018). PubMed: 30115973
  • Yang Q  et al. PRKAA1/AMPKa1-driven glycolysis in endothelial cells exposed to disturbed flow protects against atherosclerosis. Nat Commun 9:4667 (2018). PubMed: 30405100
  • Håversen L  et al. Vimentin deficiency in macrophages induces increased oxidative stress and vascular inflammation but attenuates atherosclerosis in mice. Sci Rep 8:16973 (2018). PubMed: 30451917
  • Tilley FC  et al. Retromer associates with the cytoplasmic amino-terminus of polycystin-2. J Cell Sci 131:N/A (2018). PubMed: 29724910
  • Yang R  et al. Treatment of type 2 diabetes mellitus via reversing insulin resistance and regulating lipid homeostasis in vitro and in vivo using cajanonic acid A. Int J Mol Med 42:2329-2342 (2018). PubMed: 30226559
  • Han TJ  et al. Leptin and its receptor in glucose metabolism of T-cell lymphoma. Oncol Lett 16:5838-5846 (2018). PubMed: 30333864
  • Chen YH  et al. Asymmetric PI3K Activity in Lymphocytes Organized by a PI3K-Mediated Polarity Pathway. Cell Rep 22:860-868 (2018). ICC/IF . PubMed: 29420173
  • Wang T  et al. Glycolysis is essential for chemoresistance induced by transient receptor potential channel C5 in colorectal cancer. BMC Cancer 18:207 (2018). PubMed: 29463225
  • Ioja S  et al. Nocturnal Hypoxia Improves Glucose Disposal, Decreases Mitochondrial Efficiency, and Increases Reactive Oxygen Species in the Muscle and Liver of C57BL/6J Mice Independent of Weight Change. Oxid Med Cell Longev 2018:9649608 (2018). PubMed: 29507654
  • Li Y  et al. Large Intergenic Non-coding RNA-RoR Inhibits Aerobic Glycolysis of Glioblastoma Cells via Akt Pathway. J Cancer 9:880-889 (2018). PubMed: 29581766
  • Wang F  et al. The Warburg effect in human pancreatic cancer cells triggers cachexia in athymic mice carrying the cancer cells. BMC Cancer 18:360 (2018). PubMed: 29609556
  • Chen Z  et al. MiR-3662 suppresses hepatocellular carcinoma growth through inhibition of HIF-1a-mediated Warburg effect. Cell Death Dis 9:549 (2018). PubMed: 29748591
  • Deng Y  et al. mTOR-mediated glycolysis contributes to the enhanced suppressive function of murine tumor-infiltrating monocytic myeloid-derived suppressor cells. Cancer Immunol Immunother 67:1355-1364 (2018). PubMed: 29968153
  • Femenía T  et al. Disrupted Neuroglial Metabolic Coupling after Peripheral Surgery. J Neurosci 38:452-464 (2018). PubMed: 29175959
  • Jin W  et al. Long non-coding RNA TUC338 is functionally involved in sorafenib-sensitized hepatocarcinoma cells by targeting RASAL1. Oncol Rep 37:273-280 (2017). PubMed: 27878301
  • Wang T  et al. Elevated expression of TrpC5 and GLUT1 is associated with chemoresistance in colorectal cancer. Oncol Rep 37:1059-1065 (2017). PubMed: 28000878
  • Li G  et al. Deletion of Pdcd5 in mice led to the deficiency of placenta development and embryonic lethality. Cell Death Dis 8:e2811 (2017). PubMed: 28542142
  • Kvainickas A  et al. Retromer- and WASH-dependent sorting of nutrient transporters requires a multivalent interaction network with ANKRD50. J Cell Sci 130:382-395 (2017). PubMed: 27909246
  • Nguyen A  et al. Characterization of the transcriptional and metabolic responses of pediatric high grade gliomas to mTOR-HIF-1a axis inhibition. Oncotarget 8:71597-71617 (2017). PubMed: 29069732
  • Kunisada Y  et al. Attenuation of CD4+CD25+ Regulatory T Cells in the Tumor Microenvironment by Metformin, a Type 2 Diabetes Drug. EBioMedicine 25:154-164 (2017). Flow Cyt ; Mouse . PubMed: 29066174
  • Jones N  et al. Metabolic Adaptation of Human CD4+and CD8+T-Cells to T-Cell Receptor-Mediated Stimulation. Front Immunol 8:1516 (2017). PubMed: 29170670
  • Hu L  et al. Emodin and rhein decrease levels of hypoxia-inducible factor-1a in human pancreatic cancer cells and attenuate cancer cachexia in athymic mice carrying these cells. Oncotarget 8:88008-88020 (2017). PubMed: 29152137
  • Shi W  et al. N-Myc downstream-regulated gene 2 restrains glycolysis and glutaminolysis in clear cell renal cell carcinoma. Oncol Lett 14:6881-6887 (2017). PubMed: 29163707
  • Kratchmarov R  et al. IRF4 Couples Anabolic Metabolism to Th1 Cell Fate Determination. Immunohorizons 1:156-161 (2017). Flow Cyt ; Mouse . PubMed: 28944344
  • Kanow MA  et al. Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye. Elife 6:N/A (2017). PubMed: 28901286
  • Siska PJ  et al. Mitochondrial dysregulation and glycolytic insufficiency functionally impair CD8 T cells infiltrating human renal cell carcinoma. JCI Insight 2:N/A (2017). Flow Cyt ; Human . PubMed: 28614802
  • Uri A  et al. Protection of Mice from Acute Graft-versus-Host Disease Requires CD28 Co-stimulation on Donor CD4(+) Foxp3(+) Regulatory T Cells. Front Immunol 8:721 (2017). Flow Cyt ; Mouse . PubMed: 28690612
  • Xu H  et al. PRL-3 improves colorectal cancer cell proliferation and invasion through IL-8 mediated glycolysis metabolism. Int J Oncol 51:1271-1279 (2017). PubMed: 28791350
  • Vaeth M  et al. Store-Operated Ca2+Entry Controls Clonal Expansion of T Cells through Metabolic Reprogramming. Immunity 47:664-679.e6 (2017). PubMed: 29030115
  • Ung PM  et al. Inhibitor Discovery for the Human GLUT1 from Homology Modeling and Virtual Screening. ACS Chem Biol 11:1908-16 (2016). PubMed: 27128978
  • Xu Y  et al. Glycolysis determines dichotomous regulation of T cell subsets in hypoxia. J Clin Invest 126:2678-88 (2016). PubMed: 27294526
  • Lu K  et al. Expression and clinical significance of glucose transporter-1 in pancreatic cancer. Oncol Lett 12:243-249 (2016). IHC-P ; Human . PubMed: 27347132
  • McMillan KJ  et al. Atypical parkinsonism-associated retromer mutant alters endosomal sorting of specific cargo proteins. J Cell Biol 214:389-99 (2016). PubMed: 27528657
  • Khanom R  et al. Keratin 17 Is Induced in Oral Cancer and Facilitates Tumor Growth. PLoS One 11:e0161163 (2016). PubMed: 27512993
  • Tong D  et al. The HIF/PHF8/AR axis promotes prostate cancer progression. Oncogenesis 5:e283 (2016). Human . PubMed: 27991916
  • Chen K  et al. Regulation of glucose metabolism by p62/SQSTM1 through HIF1a. J Cell Sci 129:817-30 (2016). PubMed: 26743088
  • Zhu Y  et al. An Oncogenic Virus Promotes Cell Survival and Cellular Transformation by Suppressing Glycolysis. PLoS Pathog 12:e1005648 (2016). WB, IHC-P ; Rat . PubMed: 27187079
  • Maekawa Y  et al. Notch controls the survival of memory CD4+ T cells by regulating glucose uptake. Nat Med 21:55-61 (2015). PubMed: 25501905
  • Shi S  et al. Metabolic tumor burden is associated with major oncogenomic alterations and serum tumor markers in patients with resected pancreatic cancer. Cancer Lett 360:227-33 (2015). WB ; Human . PubMed: 25687883
  • Qin W  et al. Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells. Oncotarget 6:39839-54 (2015). WB ; Human . PubMed: 26497999
  • Boyer-Di Ponio J  et al. Instruction of circulating endothelial progenitors in vitro towards specialized blood-brain barrier and arterial phenotypes. PLoS One 9:e84179 (2014). WB . PubMed: 24392113
  • Saucillo DC  et al. Leptin metabolically licenses T cells for activation to link nutrition and immunity. J Immunol 192:136-44 (2014). PubMed: 24273001
  • Caro-Maldonado A  et al. Metabolic reprogramming is required for antibody production that is suppressed in anergic but exaggerated in chronically BAFF-exposed B cells. J Immunol 192:3626-36 (2014). PubMed: 24616478
  • Cao Y  et al. Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells. PLoS One 9:e104104 (2014). WB ; Mouse . PubMed: 25090630
  • Foster R  et al. Multiple Metabolic Alterations Exist in Mutant PI3K Cancers, but Only Glucose Is Essential as a Nutrient Source. PLoS One 7:e45061 (2012). WB . PubMed: 23028762

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