Recombinant
RabMAb

Recombinant Anti-Glucose Transporter GLUT2 antibody [EPR16550] - BSA and Azide free (ab236145)

Overview

  • Product name

    Anti-Glucose Transporter GLUT2 antibody [EPR16550] - BSA and Azide free
    See all Glucose Transporter GLUT2 primary antibodies
  • Description

    Rabbit monoclonal [EPR16550] to Glucose Transporter GLUT2 - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment within Human Glucose Transporter GLUT2 aa 1-100. The exact sequence is proprietary.
    Database link: P11168

  • Positive control

    • WB: Human fetal liver, fetal kidney and pancreas lysates; HepG2 cell lysate.
  • General notes

    Ab236145 is the carrier-free version of ab192599. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    ab236145 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Applications

Our Abpromise guarantee covers the use of ab236145 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 57 kDa (predicted molecular weight: 57 kDa).

Target

  • Function

    Facilitative glucose transporter. This isoform likely mediates the bidirectional transfer of glucose across the plasma membrane of hepatocytes and is responsible for uptake of glucose by the beta cells; may comprise part of the glucose-sensing mechanism of the beta cell. May also participate with the Na(+)/glucose cotransporter in the transcellular transport of glucose in the small intestine and kidney.
  • Tissue specificity

    Liver, insulin-producing beta cell, small intestine and kidney.
  • Involvement in disease

    Fanconi-Bickel syndrome
  • Sequence similarities

    Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • Post-translational
    modifications

    N-glycosylated; required for stability and retention at the cell surface of pancreatic beta cells.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • liver antibody
    • Glucose Transporter 2 antibody
    • Glucose Transporter GLUT2 antibody
    • Glucose transporter type 2 antibody
    • Glucose transporter type 2 liver antibody
    • Glucose transporter, liver/islet antibody
    • GLUT-2 antibody
    • GLUT2 antibody
    • GTR2_HUMAN antibody
    • GTT2 antibody
    • SLC2A2 antibody
    • Solute carrier family 2 (facilitated glucose transporter) member 2 antibody
    • Solute carrier family 2 facilitated glucose transporter member 2 antibody
    • Solute carrier family 2, facilitated glucose transporter member 2 antibody
    see all

Images

  • All lanes : Anti-Glucose Transporter GLUT2 antibody [EPR16550] (ab192599) at 1/10000 dilution

    Lane 1 : Human fetal liver lysate
    Lane 2 : Human pancreas lysate
    Lane 3 : Human fetal kidney lysate
    Lane 4 : HepG2 cell lysate

    Lysates/proteins at 20 µg per lane.

    Secondary
    All lanes : Goat anti-rabbit IgG, (H+L), peroxidase conjugated at 1/1000 dilution

    Developed using the ECL technique.

    Predicted band size: 57 kDa
    Observed band size: 57 kDa



    This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab192599).

References

ab236145 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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