Anti-Glucose Transporter GLUT3 antibody (ab15311)
Key features and details
- Rabbit polyclonal to Glucose Transporter GLUT3
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-Glucose Transporter GLUT3 antibody
See all Glucose Transporter GLUT3 primary antibodies -
Description
Rabbit polyclonal to Glucose Transporter GLUT3 -
Host species
Rabbit -
Tested Applications & Species
Application Species IHC-P Human -
Immunogen
Synthetic peptide within Human Glucose Transporter GLUT3 aa 450 to the C-terminus (C terminal). The exact sequence is proprietary.
Database link: P11169 -
General notes
This product is FOR RESEARCH USE ONLY. For commercial use, please contact partnerships@abcam.com.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.60
Preservative: 0.1% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
-
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab15311 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
Application | Species |
---|---|
IHC-P |
Human
|
All applications |
Rat
|
Application | Abreviews | Notes |
---|---|---|
IHC-P | (2) |
1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
|
Notes |
---|
IHC-P
1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
-
Function
Facilitative glucose transporter. Probably a neuronal glucose transporter. -
Tissue specificity
Highly expressed in brain. Expressed in many tissues. -
Sequence similarities
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. -
Cellular localization
Membrane. - Information by UniProt
-
Database links
- Entrez Gene: 6515 Human
- Entrez Gene: 25551 Rat
- Omim: 138170 Human
- SwissProt: P11169 Human
- SwissProt: Q07647 Rat
- Unigene: 419240 Human
- Unigene: 95055 Rat
-
Alternative names
- brain antibody
- FLJ90380 antibody
- Glucose transporter type 3 antibody
see all
Images
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Glucose Transporter GLUT3 antibody (ab15311)
Formalin-fixed, paraffin-embedded human placenta tissue stained for Glucose Transporter GLUT3 using ab15311 at 1/50 dilution in immunohistochemical analysis.
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Glucose Transporter GLUT3 antibody (ab15311)ab15311 staining Glucose Transporter GLUT3 in human placenta by Immunohistochemistry (FFPE-sections).
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Glucose Transporter GLUT3 antibody (ab15311)This image is courtesy of an anonymous Abreview.
Formaldehyde-fixed, paraffin-embedded human testis tissue stained for Glucose Transporter GLUT3 using ab15311 at 1/200 dilution in immunohistochemical analysis.
Datasheets and documents
-
SDS download
-
Datasheet download
References (23)
ab15311 has been referenced in 23 publications.
- Ghezzi C et al. A high-throughput screen identifies that CDK7 activates glucose consumption in lung cancer cells. Nat Commun 10:5444 (2019). PubMed: 31784510
- Miran T et al. Modulation of glutathione promotes apoptosis in triple-negative breast cancer cells. FASEB J 32:2803-2813 (2018). PubMed: 29301945
- Mai WX et al. Cytoplasmic p53 couples oncogene-driven glucose metabolism to apoptosis and is a therapeutic target in glioblastoma. Nat Med 23:1342-1351 (2017). PubMed: 29035366
- Kuang R et al. GLUT3 upregulation promotes metabolic reprogramming associated with antiangiogenic therapy resistance. JCI Insight 2:e88815 (2017). WB ; Human . PubMed: 28138554
- Park HS et al. Hypoxia induces glucose uptake and metabolism of adipose-derived stem cells. Mol Med Rep 14:4706-4714 (2016). PubMed: 27748854