Overview

  • Product name

    Anti-Glucose Transporter GLUT4 antibody
    See all Glucose Transporter GLUT4 primary antibodies
  • Description

    Rabbit polyclonal to Glucose Transporter GLUT4
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, Flow Cytmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide aa 467-509 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Database link: P14672

  • Positive control

    • WB; Mouse heart lysates. IHC-P; Rat kidney tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab216661 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/100 - 1/1000. Predicted molecular weight: 54 kDa.
IHC-P 1/100 - 1/500.
Flow Cyt 1/100.

Target

  • Function

    Insulin-regulated facilitative glucose transporter.
  • Tissue specificity

    Skeletal and cardiac muscles; brown and white fat.
  • Involvement in disease

    Diabetes mellitus, non-insulin-dependent
  • Sequence similarities

    Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • Post-translational
    modifications

    Sumoylated.
  • Cellular localization

    Cell membrane. Endomembrane system. Cytoplasm, perinuclear region. Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized. The dileucine internalization motif is critical for intracellular sequestration.
  • Information by UniProt
  • Database links

  • Alternative names

    • insulin-responsive antibody
    • Glucose transporter GLUT 4 antibody
    • Glucose transporter type 4 antibody
    • Glucose transporter type 4 insulin responsive antibody
    • GLUT 4 antibody
    • GLUT-4 antibody
    • GLUT4 antibody
    • GTR4_HUMAN antibody
    • Insulin responsive glucose transporter type 4 antibody
    • kug antibody
    • SLC 2A4 antibody
    • SLC2A4 antibody
    • solute carrier family 2 (facilitated glucose transporter) member 4 antibody
    • Solute carrier family 2 member 4 antibody
    • Solute carrier family 2, facilitated glucose transporter member 4 antibody
    see all

Images

  • Flow Cytometry of K562 cells with ab203387 at 1/100
  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat kidney tissue labeling Glucose Transporter GLUT4 with ab216661 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

  • Anti-Glucose Transporter GLUT4 antibody (ab216661) at 1/300 dilution (overnight in 4°C) + mouse heart lysates

    Secondary
    Goat anti-rabbit IgG (H+L), HRP conjugated (90min 37°C) at 1/5000 dilution

    Predicted band size: 54 kDa

References

ab216661 has not yet been referenced specifically in any publications.

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