Overview

  • Product name

    Anti-Glucuronic Acid Epimerase/GLCE antibody
    See all Glucuronic Acid Epimerase/GLCE primary antibodies
  • Description

    Mouse polyclonal to Glucuronic Acid Epimerase/GLCE
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Full length protein corresponding to Human Glucuronic Acid Epimerase/GLCE.
    Database link: NP_056369.1

  • Positive control

    • Glucuronic Acid Epimerase/GLCE transfected 293T lysate.
  • General notes

     This product was previously labelled as Glucuronic Acid Epimerase

     

Properties

Applications

Our Abpromise guarantee covers the use of ab68714 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Detects a band of approximately 71 kDa (predicted molecular weight: 71 kDa).

Target

  • Relevance

    Glucuronic Acid Epimerase (GLCE) is responsible for epimerization of D-glucuronic acid (GlcA) to L-iduronic acid (IdoA) of Heparan sulfate (HS), which endows the nascent polysaccharide chain with the ability to bind growth factors and cytokines (Ghiselli and Agrawal, 2005 [PubMed 15853773]).
  • Cellular localization

    Golgi apparatus membrane; Single-pass type II membrane protein
  • Database links

  • Alternative names

    • D glucuronyl C5 epimerase antibody
    • GLCE antibody
    • Heparin/heparan sulfate:glucuronic acid C5 epimerase antibody
    • HSEPI antibody
    • KIAA0836 antibody
    see all

Images

  • All lanes : Anti-Glucuronic Acid Epimerase/GLCE antibody (ab68714) at 1/500 dilution

    Lane 1 : Glucuronic Acid Epimerase/GLCE transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Lane 1 : Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution
    Lane 2 : Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size: 71 kDa
    Observed band size: 71 kDa

References

This product has been referenced in:

  • Small EM  et al. MicroRNA-218 regulates vascular patterning by modulation of Slit-Robo signaling. Circ Res 107:1336-44 (2010). WB ; Human, Mouse . Read more (PubMed: 20947829) »
See 1 Publication for this product

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