• Product name

  • Description

    Rabbit polyclonal to GluK1
  • Host species

  • Tested applications

    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human GluK1 (internal sequence).
    (Peptide available as ab115358)

  • Positive control

    • rat brain tissue lysate, human brain tissue
  • General notes

     This product was previously labelled as GRIK1




Our Abpromise guarantee covers the use of ab67317 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 1 µg/ml. Detects a band of approximately 104 kDa (predicted molecular weight: 104 kDa).
IHC-P Use at an assay dependent concentration.


  • Function

    Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.
  • Tissue specificity

    Most abundant in the cerebellum and the suprachiasmatic nuclei (SCN) of the hypothalamus.
  • Sequence similarities

    Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK1 subfamily.
  • Cellular localization

    Cell membrane. Cell junction > synapse > postsynaptic cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • EAA3 antibody
    • EEA3 antibody
    • Excitatory amino acid receptor 3 antibody
    • GLR5 antibody
    • GluR-5 antibody
    • GluR5 antibody
    • GluR6 antibody
    • GluR7 antibody
    • Glutamate receptor 5 antibody
    • Glutamate receptor antibody
    • Glutamate receptor ionotropic kainate 1 antibody
    • GRIK1 antibody
    • GRIK1_HUMAN antibody
    • Human glutamate receptor GLUR5 antibody
    • ionotropic kainate 1 antibody
    • OTTHUMP00000096569 antibody
    see all


  •  ab67317 at 2.5 μg/ml staining of GluK1 in human brain tissue using IHC-P

  • Lane 1 : Anti-GluK1 antibody (ab67317) at 0.5 µg/ml
    Lane 2 : Anti-GluK1 antibody (ab67317) at 1 µg/ml

    All lanes : rat brain tissue lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 104 kDa
    Observed band size: 104 kDa
    Additional bands at: 85 kDa. We are unsure as to the identity of these extra bands.

  • Immunofluorescence of GluK1 in Human Brain cells using ab67317 at 20 ug/ml.


ab67317 has not yet been referenced specifically in any publications.

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