Overview

  • Product name

  • Description

    Rabbit polyclonal to GluK5
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, IPmore details
  • Species reactivity

    Reacts with: Rat, Rabbit
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Rat GluK5 aa 960-979 (C terminal).
    Sequence:

    KTSPPRPRPGPTGPRELTEHE

  • Positive control

    • WB: rat brain microsomal preparation IP: rabbit brain membrane extract IHC-P: Rat brain tissue.
  • General notes

     This product was previously labelled as GRIK5

     

Properties

Applications

Our Abpromise guarantee covers the use of ab32672 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 123 kDa (predicted molecular weight: 103 kDa).
IHC-P Use a concentration of 1 µg/ml.
IP Use at an assay dependent concentration.

Target

  • Function

    Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. This receptor binds kainate > quisqualate > domoate > L-glutamate >> AMPA >> NMDA = 1S,3R-ACPD.
  • Sequence similarities

    Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIK5 subfamily.
  • Cellular localization

    Cell membrane. Cell junction > synapse > postsynaptic cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • EAA 2 antibody
    • EAA2 antibody
    • Excitatory amino acid receptor 2 antibody
    • GluK5 antibody
    • GluRgamma2 antibody
    • Glutamate receptor antibody
    • Glutamate receptor KA 2 antibody
    • Glutamate receptor KA-2 antibody
    • Glutamate receptor KA2 antibody
    • Glutamate receptor, ionotropic kainate 5 [Precursor] antibody
    • Glutamate receptor, ionotropic, kainate 5 (gamma 2) antibody
    • Glutamate receptor, ionotropic, kainate 5 antibody
    • GRIK 2 antibody
    • GRIK 5 antibody
    • GRIK2 antibody
    • Grik5 antibody
    • GRIK5_HUMAN antibody
    • iGlu5 antibody
    • ionotropic kainate 5 antibody
    • KA2 antibody
    • MGC118086 antibody
    see all

Images

  • Formalin-fixed, paraffin-embedded rat brain stained for GluK5 using ab32672 at 1 μg/ml in immunohistochemical analysis.

    High energy antigen retrieval.

References

ab32672 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab32672.
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