Overview

  • Product name

  • Description

    Rabbit polyclonal to GluN2C
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Rat
    Predicted to work with: Mouse, Human
  • Immunogen

    Synthetic peptide within Human GluN2C aa 500-550 conjugated to keyhole limpet haemocyanin. The exact sequence is proprietary.
    Sequence:

    YKRADMAIGSL TINEERSEIV DFSVPFVETG ISVMVARSNG TVSPSAFLEP


    Database link: Q14957

  • Positive control

    • Rat brain tissue.
  • General notes

    Previously labelled as NMDAR2C. 

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituents: 50% Glycerol, 1% BSA
  • Concentration information loading...
  • Purity

    Protein A purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab217039 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/500.

Target

  • Function

    NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
  • Tissue specificity

    Mainly expressed in brain with predominant expression is in the cerebellum, also present in the hippocampus, amygdala, caudate nucleus, corpus callosum, subthalamic nuclei and thalamus. Detected in the heart, skeletal muscle and pancreas.
  • Sequence similarities

    Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2C/GRIN2C subfamily.
  • Cellular localization

    Cell membrane. Cell junction, synapse, postsynaptic cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • GluN2C antibody
    • Glutamate [NMDA] receptor subunit epsilon-3 antibody
    • Glutamate Receptor Ionotropic N Methyl D Aspartate 2C antibody
    • Glutamate receptor ionotropic, NMDA 2C antibody
    • Glutamate receptor, ionotropic, N methyl D aspartate 2C antibody
    • Grin2c antibody
    • N Methly D Aspartate Receptor Channel Subunit Epsilon 3 antibody
    • N Methyl D Aspartate Receptor Subtype 2C antibody
    • N methyl D aspartate receptor subunit 2C antibody
    • N-methyl D-aspartate receptor subtype 2C antibody
    • NMDAR2C antibody
    • NMDE3_HUMAN antibody
    • NR2C antibody
    • OTTHUMP00000041930 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat brain tissue labeling GluN2C with ab217039 at 1/100 dilution followed by conjugation to the secondary antibody and DAB staining.

References

ab217039 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab217039.
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