Product nameAnti-GluN2C antibody [EPR18949]
See all GluN2C primary antibodies
DescriptionRabbit monoclonal [EPR18949] to GluN2C
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Rat
Recombinant fragment within Mouse GluN2C aa 1000 to the C-terminus. The exact sequence is proprietary.
Database link: Q01098
- WB: Mouse and rat cerebellum lysates.
Previously labelled as NMDAR2C.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol, 0.05% BSA
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab182278 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Detects a band of approximately 135 kDa (predicted molecular weight: 135 kDa).|
FunctionNMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
Tissue specificityMainly expressed in brain with predominant expression is in the cerebellum, also present in the hippocampus, amygdala, caudate nucleus, corpus callosum, subthalamic nuclei and thalamus. Detected in the heart, skeletal muscle and pancreas.
Sequence similaritiesBelongs to the glutamate-gated ion channel (TC 1.A.10.1) family. NR2C/GRIN2C subfamily.
Cellular localizationCell membrane. Cell junction, synapse, postsynaptic cell membrane.
- Information by UniProt
- GluN2C antibody
- Glutamate [NMDA] receptor subunit epsilon-3 antibody
- Glutamate Receptor Ionotropic N Methyl D Aspartate 2C antibody
All lanes : Anti-GluN2C antibody [EPR18949] (ab182278) at 1/1000 dilution
Lane 1 : Mouse cerebellum lysate
Lane 2 : Rat cerebellum lysate
Lane 3 : Mouse heart lysate
Lane 4 : Rat kidney lysate
Lane 5 : Neuro-2a (Mouse neuroblastoma cell line) whole cell lysate
Lysates/proteins at 20 µg per lane.
All lanes : Goat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/100000 dilution
Predicted band size: 135 kDa
Observed band size: 135 kDa
Exposure time: 3 minutes
Blocking/Dilution buffer: 5% NFDM/TBST.
The molecular weight and tissue specificity is consistent with reference (PMID:8987814).
ab182278 has not yet been referenced specifically in any publications.