Product nameAnti-GLUT10 antibody
See all GLUT10 primary antibodies
DescriptionRabbit polyclonal to GLUT10
SpecificityThis antibody has been fully characterized for cross reactivity within the Glut family and with other cellular proteins.
Tested applicationsSuitable for: WB, ELISA, Dot blot, IPmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Rat GLUT10 (C terminal).
- Hippocampal plasma membranes.
Previously labelled as Glucose Transporter GLUT10.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservative: 0.02% Sodium azide
Stabilization buffer: contains Phosphate buffer; stabilizing proteins; cryogenic protectant and antibody stabilizer.
Concentration information loading...
PurityImmunogen affinity purified
Purification notesAntibodies are isolated on an antigen-speharose affinity column.
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
Our Abpromise guarantee covers the use of ab75440 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IP: Use 2.5µl per sample.
WB: 1/500. Predicted molecular weight: 57 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionFacilitative glucose transporter.
Tissue specificityWidely expressed; highest levels in liver and pancreas.
Involvement in diseaseDefects in SLC2A10 are the cause of arterial tortuosity syndrome (ATS) [MIM:208050]. ATS is an autosomal recessive disorder characterized by tortuosity and elongation of major arteries, often resulting in death at young age. Other typical features include aneurysms of large arteries and stenosis of the pulmonary artery, in association with facial features and several connective tissue manifestations such as soft skin and joint laxity. Histopathological findings include fragmentation of elastic fibers in the tunica media of large arteries.
Sequence similaritiesBelongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
Cellular localizationEndomembrane system. Cytoplasm > perinuclear region.
- Information by UniProt
- AA450473 antibody
- ATS antibody
- facilitated glucose transporter member 10 antibody
ab75440 has not yet been referenced specifically in any publications.