Overview

  • Product name

  • Description

    Rabbit polyclonal to GLUT12
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Flow Cyt, IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human GLUT12 aa 299-317 conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Sequence:

    FYASTVLKSVGFQSNEAAS


    Database link: Q8TD20

  • Positive control

    • Mouse heart tissue. Human LNCaP prostate cancer cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab202908 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/20 - 1/100.

ab171870 - Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.

 

IHC-P 1/50 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Use at 1/50 - 1/200 with fluorescent detection methods.

WB 1/100 - 1/1000. Predicted molecular weight: 67 kDa.

Target

  • Function

    Facilitative glucose transporter.
  • Tissue specificity

    Predominantly expressed in skeletal muscle, heart and prostate, with lower levels in brain, placenta and kidney.
  • Sequence similarities

    Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily.
  • Post-translational
    modifications

    N-glycosylated.
  • Cellular localization

    Endomembrane system. Cytoplasm > perinuclear region. Localizes primarily perinuclear region in the absence of insulin.
  • Information by UniProt
  • Database links

  • Alternative names

    • Glucose transporter type 12 antibody
    • GLUT 12 antibody
    • GLUT-12 antibody
    • GLUT12 antibody
    • GLUT8 antibody
    • GTR12_HUMAN antibody
    • SLC2A12 antibody
    • Solute carrier family 2 (facilitated glucose transporter) member 12 antibody
    • Solute carrier family 2 facilitated glucose transporter member 12 antibody
    • Solute carrier family 2 member 12 antibody
    • Solute carrier family 2, facilitated glucose transporter member 12 antibody
    see all

Images

  • Immunohistochemical analysis of formalin/PFA-fixed paraffin-embedded mouse heart tissue sections labeling GLUT12 with ab202908 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

  • Human LNCaP prostate cancer cells stained with ab202908  for 30 minutes at 4°C, followed by secondary antibody Alexa-Fluor 488 incubation for 30 minutes at 4°C in the dark.

References

ab202908 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab202908.
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