Anti-Glutaredoxin 1 antibody (ab187507)
Key features and details
- Rabbit polyclonal to Glutaredoxin 1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-Glutaredoxin 1 antibody
See all Glutaredoxin 1 primary antibodies -
Description
Rabbit polyclonal to Glutaredoxin 1 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment corresponding to Human Glutaredoxin 1.
Database link: P35754 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab187507 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/2000. Predicted molecular weight: 12 kDa.
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Notes |
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WB
1/500 - 1/2000. Predicted molecular weight: 12 kDa. |
Target
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Function
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. -
Sequence similarities
Belongs to the glutaredoxin family.
Contains 1 glutaredoxin domain. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 2745 Human
- Omim: 600443 Human
- SwissProt: P35754 Human
- Unigene: 28988 Human
- Unigene: 712696 Human
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Alternative names
- GLRX antibody
- Glrx1 antibody
- GLRX1_HUMAN antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab187507 has been referenced in 4 publications.
- Seidel K et al. Alcohol Binge Drinking Selectively Stimulates Protein S-Glutathionylation in Aorta and Liver of ApoE-/- Mice. Front Cardiovasc Med 8:649813 (2021). PubMed: 33796575
- Yi M et al. Comparative proteomic analysis identifies biomarkers for renal aging. Aging (Albany NY) 12:21890-21903 (2020). PubMed: 33159023
- Yi M et al. Glutathionylation Decreases Methyltransferase Activity of PRMT5 and Inhibits Cell Proliferation. Mol Cell Proteomics 19:1910-1920 (2020). PubMed: 32868396
- Kilanczyk E et al. S-adenosyl-L-methionine (SAMe) halts the autoimmune response in patients with primary biliary cholangitis (PBC) via antioxidant and S-glutathionylation processes in cholangiocytes. Biochim Biophys Acta Mol Basis Dis 1866:165895 (2020). PubMed: 32681864