Product nameAnti-Glutathione antibody
See all Glutathione primary antibodies
DescriptionRat polyclonal to Glutathione
Specificityab37124 targets conjugated glutathione, it doesn't recognize free glutathione.
Tested applicationsSuitable for: IHC-Pmore details
Chemical/ Small Molecule corresponding to Glutathione conjugated to Bovine Serum Albumin (BSA) (Glutaraldehyde).
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferConstituents: 50% Glycerol, ddH20
Concentration information loading...
Our Abpromise guarantee covers the use of ab37124 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use at an assay dependent concentration.
Fixation of tissue for use with these antibodies should be done with gluteraldehyde. The use of paraformaldehyde in conjunction with gluteraldehyde may improve staining results.
RelevanceGlutathione is a small peptide composed of three amino acids: cysteine, glutamic acid, and glycine and is present in tissues in concentrations as high as one millimolar. It contains an unusual peptide linkage between the amine group of cysteine and the carboxyl group of the glutamate side chain. Glutathione is involved in detoxification, it binds to toxins, such as heavy metals, solvents, and pesticides, and transforms them into a form that can be excreted in urine or bile. It is also an important antioxidant, helping to maintain the -SH groups of proteins in their reduced form. Chronic functional glutathione deficiency is associated with glucose 6-phosphate dehydrogenase deficiency, immune disorders, an increased incidence of malignancies, and in the case of HIV disease, probably accelerated pathogenesis of the disease. Acute manifestations of functional glutathione deficiency can be seen in those who have taken an overdosage of acetaminophen (paracetamol). This results in depletion of glutathione in the hepatocytes, leading to liver failure and death.
- Glutathione antibody
- GSH antibody
- Oxidised glutathione antibody
- Reduced glutathione antibody
ab37124 has not yet been referenced specifically in any publications.