Recombinant
RabMAb

Recombinant Anti-Glutathione Peroxidase 2/GPX2 antibody [EPR8175(2)] (ab140130)

Overview

  • Product name

    Anti-Glutathione Peroxidase 2/GPX2 antibody [EPR8175(2)]
    See all Glutathione Peroxidase 2/GPX2 primary antibodies
  • Description

    Rabbit monoclonal [EPR8175(2)] to Glutathione Peroxidase 2/GPX2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
    Unsuitable for: Flow Cyt,ICC or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human Glutathione Peroxidase 2/GPX2 aa 150-250 (C terminal). The exact sequence is proprietary.

  • Positive control

    • Human colon cancer and stomach lysates; Human colon tissue.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

     This product was previously labelled as Glutathione Peroxidase 2

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab140130 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 22 kDa.
IHC-P 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt,ICC or IP.
  • Target

    • Function

      Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors.
    • Tissue specificity

      Mostly in liver and gastrointestinal tract, not found in heart or kidney.
    • Sequence similarities

      Belongs to the glutathione peroxidase family.
    • Cellular localization

      Cytoplasm. Mainly cytoplasmic.
    • Information by UniProt
    • Database links

    • Alternative names

      • Gastrointestinal glutathione peroxidase antibody
      • GI GPx antibody
      • Glutathione peroxidase 2 (gastrointestinal) antibody
      • Glutathione peroxidase 2 antibody
      • Glutathione peroxidase gastrointestinal antibody
      • Glutathione peroxidase related protein 2 antibody
      • Glutathione peroxidase-gastrointestinal antibody
      • Glutathione peroxidase-related protein 2 antibody
      • GPRP antibody
      • GPRP-2 antibody
      • GPx 2 antibody
      • GPx-2 antibody
      • GPx-GI antibody
      • GPX2 antibody
      • GPX2_HUMAN antibody
      • GSHPx 2 antibody
      • GSHPx GI antibody
      • GSHPx-2 antibody
      • GSHPx-GI antibody
      see all

    Images

    • All lanes : Anti-Glutathione Peroxidase 2/GPX2 antibody [EPR8175(2)] (ab140130) at 1/1000 dilution

      Lane 1 : Human colon cancer lysate
      Lane 2 : Human stomach lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 22 kDa

    • Immunohistochemical analysis of paraffin-embedded Human colon tissue labelling Glutathione Peroxidase 2/GPX2 with ab140130 at 1/100 dilution.

    References

    This product has been referenced in:

    • Touat-Hamici Z  et al. Selenium-regulated hierarchy of human selenoproteome in cancerous and immortalized cells lines. Biochim Biophys Acta N/A:N/A (2018). Human . Read more (PubMed: 29660373) »
    • Geraghty P  et al. Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure. Mediators Inflamm 2016:9461289 (2016). Read more (PubMed: 28070146) »
    See all 2 Publications for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab140130.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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