Product nameAnti-Glutathione Peroxidase 2/GPX2 antibody [EPR8175(2)]
See all Glutathione Peroxidase 2/GPX2 primary antibodies
DescriptionRabbit monoclonal [EPR8175(2)] to Glutathione Peroxidase 2/GPX2
Tested applicationsSuitable for: WB, IHC-Pmore details
Unsuitable for: Flow Cyt,ICC or IP
Species reactivityReacts with: Human
Synthetic peptide within Human Glutathione Peroxidase 2/GPX2 aa 150-250 (C terminal). The exact sequence is proprietary.
- Human colon cancer and stomach lysates; Human colon tissue.
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
This product was previously labelled as Glutathione Peroxidase 2
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
This product is a recombinant rabbit monoclonal antibody.
Storage instructionsShipped at 4°C. Store at -20ºC.
Storage bufferPreservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
PurityTissue culture supernatant
Our Abpromise guarantee covers the use of ab140130 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Predicted molecular weight: 22 kDa.|
|IHC-P||1/100 - 1/250.|
FunctionCould play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors.
Tissue specificityMostly in liver and gastrointestinal tract, not found in heart or kidney.
Sequence similaritiesBelongs to the glutathione peroxidase family.
Cellular localizationCytoplasm. Mainly cytoplasmic.
- Information by UniProt
- Gastrointestinal glutathione peroxidase antibody
- GI GPx antibody
- Glutathione peroxidase 2 (gastrointestinal) antibody
All lanes : Anti-Glutathione Peroxidase 2/GPX2 antibody [EPR8175(2)] (ab140130) at 1/1000 dilution
Lane 1 : Human colon cancer lysate
Lane 2 : Human stomach lysate
Lysates/proteins at 10 µg per lane.
All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution
Predicted band size: 22 kDa
Immunohistochemical analysis of paraffin-embedded Human colon tissue labelling Glutathione Peroxidase 2/GPX2 with ab140130 at 1/100 dilution.
This product has been referenced in:
- Touat-Hamici Z et al. Selenium-regulated hierarchy of human selenoproteome in cancerous and immortalized cells lines. Biochim Biophys Acta N/A:N/A (2018). Human . Read more (PubMed: 29660373) »
- Geraghty P et al. Glutathione Peroxidase-1 Suppresses the Unfolded Protein Response upon Cigarette Smoke Exposure. Mediators Inflamm 2016:9461289 (2016). Read more (PubMed: 28070146) »