Anti-Glutathione Reductase antibody (ab137513)
Key features and details
- Rabbit polyclonal to Glutathione Reductase
- Suitable for: WB
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-Glutathione Reductase antibody
See all Glutathione Reductase primary antibodies -
Description
Rabbit polyclonal to Glutathione Reductase -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Rat -
Immunogen
Recombinant fragment, corresponding to a region within amino acids 164-403 of Human Glutathione Reductase (UniProt ID: P00390).
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Positive control
- A549, HeLa, HepG2, HCT116 and Mouse brain whole cell lysates.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab137513 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB | 1/500 - 1/3000. Predicted molecular weight: 56 kDa. |
Target
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Function
Maintains high levels of reduced glutathione in the cytosol. -
Sequence similarities
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. -
Domain
Each subunit can be divided into 4 domains that are consecutive along the polypeptide chain. Domains 1 and 2 bind FAD and NADPH, respectively. Domain 4 forms the interface. -
Cellular localization
Cytoplasm and Mitochondrion. - Information by UniProt
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Database links
- Entrez Gene: 2936 Human
- Entrez Gene: 14782 Mouse
- Entrez Gene: 116686 Rat
- Omim: 138300 Human
- SwissProt: P00390 Human
- SwissProt: P47791 Mouse
- SwissProt: P70619 Rat
- Unigene: 271510 Human
see all -
Alternative names
- GLR1 antibody
- GLUR antibody
- Glutathione reductase antibody
see all
Images
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Anti-Glutathione Reductase antibody (ab137513) at 1/1000 dilution + Mouse brain whole cell lysate at 50 µg
Predicted band size: 56 kDa
10% SDS PAGE -
Anti-Glutathione Reductase antibody (ab137513) at 1/1000 dilution + HCT116 whole cell lysate at 30 µg
Predicted band size: 56 kDa
References (1)
ab137513 has been referenced in 1 publication.
- Gu Y et al. Involvement of Kruppel-like factor 9 in bleomycin-induced pulmonary toxicity. Mol Med Rep 12:5262-6 (2015). PubMed: 26133229