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    glutathione-reductase-antibody-ap-mab0866-ab106843.pdf

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Signal Transduction Metabolism Mitochondrial
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Anti-Glutathione Reductase antibody [AP-MAB0866] (ab106843)

  • Datasheet
  • SDS
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Key features and details

  • Rat monoclonal [AP-MAB0866] to Glutathione Reductase
  • Reacts with: Mouse
  • Isotype: IgG2

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Secondary
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Goat Anti-Rat IgG H&L (Alexa Fluor® 488) (ab150157)
Protein
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Recombinant human Glutathione Reductase protein (ab82730)

View more associated products

Overview

  • Product name

    Anti-Glutathione Reductase antibody [AP-MAB0866]
    See all Glutathione Reductase primary antibodies
  • Description

    Rat monoclonal [AP-MAB0866] to Glutathione Reductase
  • Host species

    Rat
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    Mouse spontaneous T lymphoma line TK1

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    Constituent: PBS
  • Concentration information loading...
  • Purity

    Protein A purified
  • Purification notes

    The IgG fraction of culture supernatant was purified by Protein A affinity chromatography and 0.2 µm filtered. Extremely low level of LPS (< 0.002EU/µg IgG)
  • Clonality

    Monoclonal
  • Clone number

    AP-MAB0866
  • Isotype

    IgG2
  • Research areas

    • Signal Transduction
    • Metabolism
    • Mitochondrial
    • Cell Biology
    • Other Antibodies
    • Oxidative Stress
    • Metabolism
    • Pathways and Processes
    • Mitochondrial Metabolism
    • Mitochondrial markers
    • Metabolism
    • Pathways and Processes
    • Redox metabolism
    • Oxidative stress
    • Metabolism
    • Types of disease
    • Cancer

Associated products

  • Compatible Secondaries

    • Goat Anti-Rat IgG H&L (Alexa Fluor® 488) (ab150157)
    • Goat Anti-Rat IgG H&L (HRP) (ab205720)
  • Recombinant Protein

    • Recombinant human Glutathione Reductase protein (ab82730)

Target

  • Function

    Maintains high levels of reduced glutathione in the cytosol.
  • Sequence similarities

    Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  • Domain

    Each subunit can be divided into 4 domains that are consecutive along the polypeptide chain. Domains 1 and 2 bind FAD and NADPH, respectively. Domain 4 forms the interface.
  • Cellular localization

    Cytoplasm and Mitochondrion.
  • Target information above from: UniProt accession P00390 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 14782 Mouse
    • SwissProt: P47791 Mouse
    • Unigene: 283573 Mouse
    • Alternative names

      • GLR1 antibody
      • GLUR antibody
      • Glutathione reductase antibody
      • Glutathione reductase mitochondrial antibody
      • Glutathione reductase, mitochondrial antibody
      • GR antibody
      • Gr1 antibody
      • GRase antibody
      • GRD 1 antibody
      • GRD1 antibody
      • GSHR_HUMAN antibody
      • GSR antibody
      • MGC78522 antibody
      see all

    Protocols

    • Flow cytometry protocols
    • Immunohistochemistry protocols

    Click here to view the general protocols

    Datasheets and documents

    • SDS download

    • Datasheet download

      Download

    References (0)

    Publishing research using ab106843? Please let us know so that we can cite the reference in this datasheet.

    ab106843 has not yet been referenced specifically in any publications.

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