Anti-Glutathione S Transferase mu antibody (ab53942)
Key features and details
- Goat polyclonal to Glutathione S Transferase mu
- Suitable for: ICC/IF, IP, WB
- Reacts with: Mouse, Rat, Rabbit, Hamster, Human
- Isotype: IgG
Overview
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Product name
Anti-Glutathione S Transferase mu antibody
See all Glutathione S Transferase mu primary antibodies -
Description
Goat polyclonal to Glutathione S Transferase mu -
Host species
Goat -
Specificity
ab53942 is specific for Glutathione S Transferase (GST) mu. It reacts with subtype 3-3 (M1) and subtype 4-4 (M2). -
Tested applications
Suitable for: ICC/IF, IP, WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Rabbit, Hamster, Human -
Immunogen
Full length native protein (purified) Rat Glutathione S Transferase mu.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.7% BSA -
Concentration information loading...
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Purity
IgG fraction -
Purification notes
IgG fraction was prepared from the antisera using the caprylic acid precipitation method. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab53942 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC/IF |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration. PubMed: 23741294
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WB | (2) |
1/3000. Detects a band of approximately 33 kDa (predicted molecular weight: 26 kDa).
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Notes |
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ICC/IF
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. PubMed: 23741294 |
WB
1/3000. Detects a band of approximately 33 kDa (predicted molecular weight: 26 kDa). |
Target
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Function
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. -
Tissue specificity
Liver (at protein level). -
Sequence similarities
Belongs to the GST superfamily. Mu family.
Contains 1 GST C-terminal domain.
Contains 1 GST N-terminal domain. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 2944 Human
- Entrez Gene: 14862 Mouse
- Entrez Gene: 24423 Rat
- Omim: 138350 Human
- SwissProt: P09488 Human
- SwissProt: P10649 Mouse
- SwissProt: P04905 Rat
- Unigene: 301961 Human
see all -
Alternative names
- Glutathione S alkyltransferase antibody
- Glutathione S aralkyltransferase antibody
- Glutathione S aryltransferase antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (10)
ab53942 has been referenced in 10 publications.
- Shearn CT et al. The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease. PLoS One 17:e0276879 (2022). PubMed: 36378690
- Kano SI et al. Glutathione S-transferases promote proinflammatory astrocyte-microglia communication during brain inflammation. Sci Signal 12:N/A (2019). PubMed: 30783009
- Zimmerman AD et al. Changes in hepatic phase I and phase II biotransformation enzyme expression and glutathione levels following atrazine exposure in female rats. Xenobiotica 48:867-881 (2018). PubMed: 28882082
- Kuan-Hong W & Bai-Zhou L Plumbagin protects against hydrogen peroxide-induced neurotoxicity by modulating NF-?B and Nrf-2. Arch Med Sci 14:1112-1118 (2018). PubMed: 30154895
- Gleixner AM et al. Astrocytes Surviving Severe Stress Can Still Protect Neighboring Neurons from Proteotoxic Injury. Mol Neurobiol 53:4939-60 (2016). PubMed: 26374549
- Shelton LM et al. Integrated transcriptomic and proteomic analyses uncover regulatory roles of Nrf2 in the kidney. Kidney Int 88:1261-1273 (2015). WB ; Mouse . PubMed: 26422507
- Klaus A et al. Glutathione S-Transferases Interact with AMP-Activated Protein Kinase: Evidence for S-Glutathionylation and Activation In Vitro. PLoS One 8:e62497 (2013). IP ; Rat . PubMed: 23741294
- Ochiai H et al. Glutathione S-transferase π complexes with and stimulates Na⁺,K⁺-ATPase. J Mol Recognit 26:32-7 (2013). PubMed: 23280615
- Zhang J et al. Proteomic profiling of potential molecular targets of methyl-selenium compounds in the transgenic adenocarcinoma of mouse prostate model. Cancer Prev Res (Phila Pa) 3:994-1006 (2010). WB . PubMed: 20647336
- Hardwick RN et al. Diversity in antioxidant response enzymes in progressive stages of human nonalcoholic fatty liver disease. Drug Metab Dispos 38:2293-301 (2010). WB ; Human . PubMed: 20805291