Product nameAnti-Glycogen synthase 1/GYS1 antibody
See all Glycogen synthase 1/GYS1 primary antibodies
DescriptionRabbit polyclonal to Glycogen synthase 1/GYS1
Tested applicationsSuitable for: WB, IHC-P, ICC/IFmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Recombinant fragment corresponding to Human Glycogen synthase 1/GYS1.
Database link: P13807
- IHC-P: Human heart tissue. ICC/IF: HeLa cells. WB: HeLa, HEK-293T, BT-474 and mouse heart extract.
This product was previously labelled as Glycogen synthase 1
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.3
Preservative: 0.02% Sodium azide
Concentration information loading...
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
Our Abpromise guarantee covers the use of ab230422 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/20000. Predicted molecular weight: 84 kDa.|
|ICC/IF||1/50 - 1/100.|
FunctionTransfers the glycosyl residue from UDP-Glc to the non-reducing end of alpha-1,4-glucan.
PathwayGlycan biosynthesis; glycogen biosynthesis.
Involvement in diseaseDefects in GYS1 are the cause of muscle glycogen storage disease type 0 (GSD0b) [MIM:611556]; also known as muscle glycogen synthase deficiency. GSD0b is a metabolic disorder characterized by fasting hypoglycemia presenting in infancy or early childhood. The role of muscle glycogen is to provide critical energy during bursts of activity and sustained muscle work.
Sequence similaritiesBelongs to the glycosyltransferase 3 family.
- Information by UniProt
- Glycogen [starch] synthase antibody
- Glycogen synthase 1 (muscle) antibody
- Glycogen synthase 1 antibody
All lanes : Anti-Glycogen synthase 1/GYS1 antibody (ab230422) at 1/500 dilution
Lane 1 : HeLa (Human epithelial cell line from cervix adenocarcinoma) cell extracts
Lane 2 : HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) cell extracts
Lane 3 : BT-474 (Human ductal breast epithelial tumor cell line) cell extracts
Lane 4 : Mouse heart extracts
Developed using the ECL technique.
Predicted band size: 84 kDa
HeLa (Human epithelial cell line from cervix adenocarcinoma) cells stained for Glycogen synthase 1/GYS1 using ab230422 (green) at a dilution of 1/50 in ICC/IF.
Nuclear counterstain: DAPI (blue).
Formalin-fixed, paraffin-embedded human heart tissue stained for Glycogen synthase 1/GYS1 with ab230422 at a 1/200 dilution in immunohistochemical analysis.
ab230422 has not yet been referenced specifically in any publications.