Recombinant Anti-Glycophorin C/GPC antibody [EPR4115] (ab108619)
![Western blot - Anti-Glycophorin C/GPC antibody [EPR4115] (ab108619)](https://www.abcam.com/ps/products/108/ab108619/Images/ab108619-121353-anti-glycophorin-c-antibody-epr4115-western-blot.jpg "Western blot - Anti-Glycophorin C/GPC antibody [EPR4115] (ab108619)")
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR4115] to Glycophorin C/GPC
- Suitable for: WB
- Reacts with: Human
Overview
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Product name
Anti-Glycophorin C/GPC antibody [EPR4115]
See all Glycophorin C/GPC primary antibodies -
Description
Rabbit monoclonal [EPR4115] to Glycophorin C/GPC -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species WB Human
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Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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Positive control
- TF1 and K562 cell lysates.
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General notes
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
This product was previously labelled as Glycophorin C
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
Storage buffer
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading... -
Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR4115 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab108619 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Tested applications are guaranteed to work and covered by our Abpromise guarantee.
Predicted to work for this combination of applications and species but not guaranteed.
Does not work for this combination of applications and species.
| Application | Species |
|---|---|
| WB |
Human
|
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/1000 - 1/10000. Predicted molecular weight: 14 kDa.
|
| Notes |
|---|
|
WB
1/1000 - 1/10000. Predicted molecular weight: 14 kDa. |
Target
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Function
This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells. -
Tissue specificity
Glycophorin-C is expressed in erythrocytes. Glycophorin-D is ubiquitous. -
Sequence similarities
Belongs to the glycophorin-C family. -
Cellular localization
Cell membrane. Linked to the membrane via band 4.1. - Information by UniProt
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Database links
- Entrez Gene: 2995 Human
- Omim: 110750 Human
- SwissProt: P04921 Human
- Unigene: 59138 Human
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Alternative names
- CD236 antibody
- CD236R antibody
- GE antibody
see all
Images
-
Western blot - Anti-Glycophorin C/GPC antibody [EPR4115] (ab108619)All lanes : Anti-Glycophorin C/GPC antibody [EPR4115] (ab108619) at 1/1000 dilution
Lane 1 : TF1 cell lysates
Lane 2 : K562 cell lysates
Lysates/proteins at 10 µg per lane.
Predicted band size: 14 kDa -
![Anti-Glycophorin C/GPC antibody [EPR4115] (ab108619)](https://www.abcam.com/ps/products/108/ab108619/Images/ab108619-2-benefits-of-recombinant-antibodies.png)
Anti-Glycophorin C/GPC antibody [EPR4115] (ab108619)
Datasheets and documents
References (1)
ab108619 has been referenced in 1 publication.
- Maxwell P et al. Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation. Br J Haematol 168:429-42 (2015). PubMed: 25283956
