Overview

  • Product name

    Glycyrrhizic acid, Antiviral agent
  • Description

    Antiviral agent. 11β-hydroxysteroid dehydrogenase inhibtior.
  • Biological description

    Antiviral agent. 11β-hydroxysteroid dehydrogenase inhibitior. Increases glyoxalase-1 activity and expression. Shows anti-inflammatory, antiviral, antimicrobial, antioxidative, anticancer, immunomodulatory, hepatoprotective and cardioprotective effects in vivo. Orally active.
  • CAS Number

    1405-86-3
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    3-O-(2-O-β-D-Glucopyranuronosyl-α-D-glucopyranuronosyl)-18β-glycyrrhetinic acid
  • Molecular weight

    822.93
  • Molecular formula

    C42H62O16
  • PubChem identifier

    53312460
  • Storage instructions

    Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 20 mM, in DMSO to 100 mM and in ethanol to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1[C@@H](C([C@]2([C@](C1)([C@]3([C@@](CC2)([C@]4(C(=CC3=O)[C@@]5([C@@](CC4)(CC[C@@](C5)(C(O)=O)C)C)[H])C)C)[H])C)[H])(C)C)O[C@H]6O[C@@H]([C@H]([C@@H]([C@@H]6O[C@@H]7O[C@@H]([C@H]([C@@H]([C@@H]7O)O)O)C(O)=O)O)O)C(O)=O
  • Source

    Glycyrrhiza glabra

  • Research areas

References

This product has been referenced in:

  • Wang ZH  et al. Glycyrrhizic acid attenuated glycative stress in kidney of diabetic mice through enhancing glyoxalase pathway. Mol Nutr Food Res : (2014). Read more (PubMed: 24585461) »
  • Wen J  et al. Comparative pharmacokinetic study of four major components after oral administration of pure compounds, herbs and Si-Ni-San to rats. Xenobiotica : (2014). Read more (PubMed: 24641106) »
  • Asl MN & Hosseinzadeh H Review of pharmacological effects of Glycyrrhiza sp. and its bioactive compounds. Phytother Res 22:709-24 (2008). Read more (PubMed: 18446848) »

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