Anti-GMPS antibody (ab220272)
Key features and details
- Rabbit polyclonal to GMPS
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GMPS antibody
See all GMPS primary antibodies -
Description
Rabbit polyclonal to GMPS -
Host species
Rabbit -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Orangutan -
Immunogen
Recombinant fragment corresponding to Human GMPS aa 1-200.
Database link: P49915 -
Positive control
- MCF7 cells.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
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Related Products
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab220272 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
ICC/IF |
Use a concentration of 0.25 - 2 µg/ml.
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Notes |
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ICC/IF
Use a concentration of 0.25 - 2 µg/ml. |
Target
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Function
Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division. -
Pathway
Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1. -
Involvement in disease
Note=A chromosomal aberration involving GMPS is found in acute myeloid leukemias. Translocation t(3,11)(q25,q23) with MLL. -
Sequence similarities
Contains 1 glutamine amidotransferase type-1 domain.
Contains 1 GMP-binding domain. -
Cellular localization
Cytoplasm. - Information by UniProt
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Database links
- Entrez Gene: 8833 Human
- Entrez Gene: 229363 Mouse
- Entrez Gene: 295088 Rat
- Omim: 600358 Human
- SwissProt: P49915 Human
- SwissProt: Q3THK7 Mouse
- SwissProt: Q5RA96 Orangutan
- SwissProt: Q4V7C6 Rat
see all -
Alternative names
- GATD7 antibody
- Glutamine amidotransferase antibody
- GMP synthase [glutamine hydrolyzing] antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab220272 has not yet been referenced specifically in any publications.