Anti-GMPR1 antibody - C-terminal (ab171326)

Overview

  • Product name
    Anti-GMPR1 antibody - C-terminal
    See all GMPR1 primary antibodies
  • Description
    Rabbit polyclonal to GMPR1 - C-terminal
  • Host species
    Rabbit
  • Tested applications
    Suitable for: IHC-P, WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human GMPR1 aa 237-267 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.
    Database link: P36959

  • Positive control
    • Transfected 293 cell lysate and Human breast carcinoma tissue

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity
    Ammonium Sulphate Precipitation
  • Purification notes
    ab171326 is purified by saturated ammonium sulfate (SAS) precipitation followed by dialysis against PBS.
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab171326 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/10 - 1/50. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/50 - 1/100. Predicted molecular weight: 37 kDa.

Target

  • Function
    Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
  • Sequence similarities
    Belongs to the IMPDH/GMPR family.
  • Information by UniProt
  • Database links
  • Alternative names
    • GMP reductase 1 antibody
    • Gmpr antibody
    • GMPR1_HUMAN antibody
    • Guanosine 5' monophosphate oxidoreductase 1 antibody
    • Guanosine 5''-monophosphate oxidoreductase 1 antibody
    • Guanosine monophosphate reductase 1 antibody
    • guanosine monophosphate reductase antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed and paraffin embedded Human breast carcinoma labeling GMPR1 using ab171326 at a 1/10 dilution, followed by peroxidase conjugation of the secondary antibody and DAB staining.

  • All lanes : Anti-GMPR1 antibody - C-terminal (ab171326) at 1/50 dilution

    Lane 1 : 293 cell lysate
    Lane 2 : 293 cell lysate transiently transfected with the GMPR1 gene

    Lysates/proteins at 2 µg per lane.

    Predicted band size: 37 kDa

References

ab171326 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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