Anti-GNL1 antibody (ab245633)

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Overview

  • Product name

    Anti-GNL1 antibody
    See all GNL1 primary antibodies

  • Description

    Rabbit polyclonal to GNL1

  • Host species

    Rabbit

  • Tested applications

    Suitable for: IPmore details
    Unsuitable for: WB

  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Chimpanzee, Orangutan

  • Immunogen

    Synthetic peptide within Human GNL1 aa 1-50. The exact sequence is proprietary. NP_005266.2
    Database link: P36915

  • Positive control

    • IP: HeLa whole cell lysate.

Properties

  • Form

    Liquid

  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

  • Storage buffer

    Preservative: 0.09% Sodium azide
    Constituent: Tris citrate/phosphate

    pH 7 to 8
  • Concentration information loading...

  • Purity

    Immunogen affinity purified

  • Purification notes

    ab245633 was affinity purified using an epitope specific to GNL1 immobilized on solid support.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Research areas

Applications

Our Abpromise guarantee covers the use of ab245633 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IP Use at 5-10 µg/mg of lysate.
  • Application notes
    Is unsuitable for WB.

    • Target

    • Function

      Possible regulatory or functional link with the histocompatibility cluster.

    • Sequence similarities

      Belongs to the MMR1/HSR1 GTP-binding protein family.
      Contains 1 G (guanine nucleotide-binding) domain.

    • Domain

      In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.

    • Post-translational
      modifications

      Phosphorylated upon DNA damage, probably by ATM or ATR.
    • Information by UniProt

    • Database links

      see all

    • Alternative names

      • Gnl1 antibody
      • GNL1_HUMAN antibody
      • GTP binding protein HSR1 antibody
      • GTP-binding protein HSR1 antibody
      • Guanine nucleotide binding protein like 1 antibody
      • Guanine nucleotide-binding protein-like 1 antibody
      • HSR1 antibody
      • HSR1 GTP binding protein antibody
      see all

    Images

    • Immunoprecipitation - Anti-GNL1 antibody (ab245633)
      Immunoprecipitation - Anti-GNL1 antibody (ab245633)

      GNL1 was immunoprecipitated from HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate (1 mg for IP, 20% of IP loaded) with ab245633 at 10 µg/mg lysate. Western blot was performed from the immunoprecipitate using a different Anti-GNL1 antibody at 0.4 µg/ml.

      Lane 1: ab245633 IP in HeLa whole cell lysate.
      Lane 2: Control IgG IP in HeLa whole cell lysate.

      Detection: Chemiluminescence with exposure time of 30 seconds.

    References

    ab245633 has not yet been referenced specifically in any publications.

    Publishing research using ab245633? Please let us know so that we can cite the reference in this datasheet.

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