Overview

  • Product name

    Anti-GNLY/Granulysin antibody
    See all GNLY/Granulysin primary antibodies
  • Description

    Rabbit polyclonal to GNLY/Granulysin
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Recombinant fragment corresponding to Human GNLY/Granulysin aa 23-83.
    Sequence:

    RLSPEYYDLARAHLRDEEKSCPCLAQEGPQGDLLTKTQELGRDYRTCLTI VQKLKKMVDKP


    Database link: P22749

  • Positive control

    • Human spleen tissue.
  • General notes

     This product was previously labelled as GNLY

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.20
    Preservative: 0.02% Sodium azide
    Constituents: 59% PBS, 40% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab204594 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/1000 - 1/2500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Antimicrobial protein that kills intracellular pathogens. Active against a broad range of microbes, including Gram-positive and Gram-negative bacteria, fungi, and parasites. Kills Mycobacterium tuberculosis.
  • Tissue specificity

    Expressed in natural killer and T-cells.
  • Sequence similarities

    Contains 1 saposin B-type domain.
  • Post-translational
    modifications

    A 9 kDa form is produced by proteolytic processing of a 15 kDa protein.
  • Cellular localization

    Secreted. Located in the cytotoxic granules of T-cells, which are released upon antigen stimulation.
  • Information by UniProt
  • Database links

  • Alternative names

    • 519 antibody
    • D2S69E antibody
    • GNLY antibody
    • GNLY_HUMAN antibody
    • Granulysin antibody
    • Granulysin precursor antibody
    • LAG 2 antibody
    • LAG2 antibody
    • Lymphocyte activation gene 2 antibody
    • Lymphokine LAG 2 antibody
    • Lymphokine LAG-2 antibody
    • NKG 5 antibody
    • NKG5 antibody
    • Protein NKG5 antibody
    • T cell activation protein 519 antibody
    • T lymphocyte activation gene 519 antibody
    • T-cell activation protein 519 antibody
    • TLA519 antibody
    see all

Images

  • Immunohistochemical analysis of Paraffin-embedded Human spleen tissue labeling GNLY/Granulysin with ab204594 at 1/1000 dilution.

References

ab204594 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab204594.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up