Overview

  • Product name

    Anti-GP2 antibody [GP2/1712]
    See all GP2 primary antibodies
  • Description

    Mouse monoclonal [GP2/1712] to GP2
  • Host species

    Mouse
  • Tested applications

    Suitable for: Protein Array, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Does not react with: Mouse
  • Immunogen

    Recombinant fragment within Human GP2 aa 35-179. The exact sequence is proprietary.
    Database link: P55259

  • Positive control

    • Human pancreas tissue.
  • General notes

    Protein previously labeled as Glycoprotein 2 (zymogen granule membrane).

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.05% Sodium azide
    Constituents: 99% PBS, 0.05% BSA
  • Concentration information loading...
  • Purity

    Protein G purified
  • Purification notes

    ab218410 was purified from Bioreactor Concentrate by Protein A/G.
  • Clonality

    Monoclonal
  • Clone number

    GP2/1712
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab218410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Protein Array Use at an assay dependent concentration.
IHC-P Use a concentration of 1 - 2 µg/ml. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

(Primary incubation for 30 minutes at RT).

Target

  • Tissue specificity

    Pancreatic secretory (zymogen) granule.
  • Sequence similarities

    Contains 1 EGF-like domain.
    Contains 1 ZP domain.
  • Cellular localization

    Cell membrane. Secreted. Secreted after cleavage in the pancreatic juice.
  • Information by UniProt
  • Database links

  • Alternative names

    • DKFZp779K0533 antibody
    • Glycoprotein 2 (zymogen granule membrane) antibody
    • GP2 antibody
    • GP2_HUMAN antibody
    • Pancreatic secretory granule membrane major glycoprotein GP2 antibody
    • Pancreatic zymogen granule membrane associated protein GP2 antibody
    • Pancreatic zymogen granule membrane protein GP-2 antibody
    • ZAP75 antibody
    see all

Images

  • ab218410 was tested in protein array against over 19000 different full-length human proteins.
    Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.
    A MAb is specific to its intended target if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human pancreas tissue labeling GP2 with ab218410 at 2 µg/ml.

References

This product has been referenced in:

  • Michel O  et al. Electroporation with Cisplatin against Metastatic Pancreatic Cancer: In Vitro Study on Human Primary Cell Culture. Biomed Res Int 2018:7364539 (2018). Read more (PubMed: 29750170) »
See 1 Publication for this product

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