Key features and details
- Rabbit polyclonal to gp78
- Suitable for: ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-gp78 antibody
See all gp78 primary antibodies
DescriptionRabbit polyclonal to gp78
Tested applicationsSuitable for: ICC/IFmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
- ICC/IF: A549 (human lung carcinoma cell line) cells.
Previously labelled as AMFR.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab222051 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 0.25 - 2 µg/ml.
Fixation/Permeabilization: PFA/Triton X-100.
FunctionE3 ubiquitin-protein ligase which can target both itself and other proteins including CD3D and APOB for proteasomal degradation. Mediates polyubiquitination of CYP3A4. Specific receptor for the autocrine motility factor. Mediates tumor invasion and metastasis. Component of a complex required to couple deglycosylation and proteasome-mediated degradation of misfolded proteins in the endoplasmic reticulun that are retrotranslocated in the cytosol. Promotes ubiquitination of misfolded proteins such as mutant CFTR; proposed to mediate sequential ubiquitination by recognizing already ubiquitin-conjugated substrates and to cooperate with E3 ubiquitin-protein ligase RNF5.
PathwayProtein modification; protein ubiquitination.
Sequence similaritiesContains 1 CUE domain.
Contains 1 RING-type zinc finger.
Cellular localizationEndoplasmic reticulum membrane.
- Information by UniProt
- AMF receptor antibody
- AMF receptor isoform 1 antibody
- AMF receptor isoform 2 antibody
ab222051 has not yet been referenced specifically in any publications.