Anti-GPCR GPR116 antibody (ab136262)
Key features and details
- Rabbit polyclonal to GPCR GPR116
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GPCR GPR116 antibody
See all GPCR GPR116 primary antibodies -
Description
Rabbit polyclonal to GPCR GPR116 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Synthetic peptide corresponding to Human GPCR GPR116 aa 30-60 (N terminal). JMH Called Assay Biotech for immunogen range 24 March 2017
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Positive control
- HeLa cell lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20ºC. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
PBS is without Mg2+ and Ca2+. -
Concentration information loading... -
Purity
Immunogen affinity purified -
Purification notes
ab136262 was affinity-purified from rabbit antiserum by immunogenic peptide affinity-chromatography. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab136262 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/500 - 1/1000. Predicted molecular weight: 149 kDa.
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| Notes |
|---|
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WB
1/500 - 1/1000. Predicted molecular weight: 149 kDa. |
Target
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Function
May have a role in the regulation of acid-base balance. -
Sequence similarities
Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
Contains 1 GPS domain.
Contains 3 Ig-like (immunoglobulin-like) domains.
Contains 1 SEA domain. -
Post-translational
modificationsProteolytically cleaved into 2 highly conserved sites: one in the SEA domain and the other in the stalk domain region preceding the first transmembrane. The later 2 subunits, the extracellular subunit and the seven-transmembrane subunit, remain tightly associated and non-covalently linked. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 221395 Human
- SwissProt: Q8IZF2 Human
- Unigene: 362806 Human
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Alternative names
- DKFZp564O1923 antibody
- FLJ90640 antibody
- G protein coupled receptor 116 antibody
see all
Images
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Western blot - Anti-GPCR GPR116 antibody (ab136262)Anti-GPCR GPR116 antibody (ab136262) at 1/500 dilution + HeLa cell lysate at 30 µg
Predicted band size: 149 kDa
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab136262 has been referenced in 1 publication.
- Wang C et al. MiR-511-5p functions as a tumor suppressor and a predictive of prognosis in colorectal cancer by directly targeting GPR116. Eur Rev Med Pharmacol Sci 23:6119-6130 (2019). PubMed: 31364112