Overview

  • Product name

    Anti-GPCR GPR124 antibody - N-terminal
    See all GPCR GPR124 primary antibodies
  • Description

    Rabbit polyclonal to GPCR GPR124 - N-terminal
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Dog, Monkey, Gorilla, Common marmoset, Elephant
  • Immunogen

    Synthetic 19 amino acid peptide from the N terminal extracellular domain of Human GPCR GPR124.

  • Positive control

    • Human colon carcinoma, neoplastic cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab150522 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 2 - 5 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube.
  • Tissue specificity

    Expressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 1 GPS domain.
    Contains 1 Ig-like (immunoglobulin-like) domain.
    Contains 4 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • Domain

    Binds to DLG1 through its PDZ-binding motif.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • DKFZp434C211 antibody
    • DKFZp434J0911 antibody
    • FLJ14390 antibody
    • G protein coupled receptor 124 antibody
    • G-protein coupled receptor 124 antibody
    • GP124_HUMAN antibody
    • GPR 124 antibody
    • Gpr124 antibody
    • KIAA1531 antibody
    • TEM 5 antibody
    • TEM5 antibody
    • Tumor endothelial marker 5 antibody
    • Tumor endothelial marker 5 precursor antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human colon carcinoma, neoplastic cells labelling GPCR GPR124 with ab150522 at 5 µg/ml.

References

ab150522 has not yet been referenced specifically in any publications.

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