Overview

  • Product name

    Anti-GPCR GPR126 antibody - C-terminal
    See all GPCR GPR126 primary antibodies
  • Description

    Rabbit polyclonal to GPCR GPR126 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human GPCR GPR126 (C terminal). The exact sequence is proprietary. Carrier-protein conjugated.
    Database link: Q86SQ4

  • Positive control

    • WB: HEK-293T whole cell and membrane extracts.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.025% Proclin
    Constituents: PBS, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab229583 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000.

Target

  • Function

    Orphan receptor. May be required for normal differentiation of promyelinating Schwann cells and for normal myelination of axons. Signals probably through G-proteins to transiently elevate cAMP levels.
  • Tissue specificity

    Expressed in placenta and to a lower extent in pancreas and liver. Detected in aortic endothelial cells but not in skin microvascular endothelial cells.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
    Contains 1 CUB domain.
    Contains 1 GPS domain.
    Contains 1 pentaxin domain.
  • Post-translational
    modifications

    Proteolytically cleaved into 2 conserved sites: one in the GPS domain (S1 site) and the other in the middle of the extracellular domain (S2 site). The proteolytic cleavage at S1 site generates an extracellular subunit and a seven-transmembrane subunit. Furin is involved in the cleavage of the S2 site generating a soluble fragment. Processing at the GPS domain occurred independent of and probably prior to the cleavage at the S2 site.
  • Cellular localization

    Cell membrane. Detected on the cell surface of activated but not resting umbilical vein.
  • Information by UniProt
  • Database links

  • Alternative names

    • adhesion G protein coupled receptor G6 antibody
    • APG1 antibody
    • Developmentally regulated G protein coupled receptor antibody
    • Developmentally regulated G-protein-coupled receptor antibody
    • dj287g14.2 antibody
    • DREG antibody
    • G protein coupled receptor 126 antibody
    • G-protein coupled receptor 126 antibody
    • GP126_HUMAN antibody
    • GPR126 antibody
    • HBV PreS1 transactivated protein 2 antibody
    • HBV PreS1-transactivated protein 2 antibody
    • LCCS9 antibody
    • OTTHUMP00000017320 antibody
    • OTTHUMP00000237093 antibody
    • OTTHUMP00000237094 antibody
    • OTTHUMP00000237115 antibody
    • PR126 antibody
    • Probable G protein coupled receptor 126 [Precursor] antibody
    • Probable G protein coupled receptor 126 antibody
    • Probable G-protein coupled receptor 126 [Precursor] antibody
    • Probable G-protein coupled receptor 126 antibody
    • PS1TP2 antibody
    • Vascular inducible G protein coupled receptor antibody
    • Vascular inducible G protein-coupled receptor antibody
    • VIGR antibody
    see all

Images

  • All lanes : Anti-GPCR GPR126 antibody - C-terminal (ab229583) at 1/500 dilution

    Lane 1 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell extract
    Lane 2 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) membrane extract

    Lysates/proteins at 30 µg per lane.


    5% SDS-PAGE gel.

References

ab229583 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab229583.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up