Anti-GPCR GPR14 antibody - N-terminal (ab150584)

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Overview

  • Product name

    Anti-GPCR GPR14 antibody - N-terminal
    See all GPCR GPR14 primary antibodies

  • Description

    Rabbit polyclonal to GPCR GPR14 - N-terminal

  • Host species

    Rabbit

  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.

  • Tested applications

    Suitable for: IHC-Pmore details

  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Monkey

  • Immunogen

    A 20 amino acid sythetic peptide from the N terminal extracellular domain of Human GPCR GPR14 (NP_061822.1).

  • Positive control

    • Human pancreas (acinar epithelium) tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab150584 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 6 - 11 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.

  • Tissue specificity

    Most abundant expression in the heart and pancreas.

  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.

  • Cellular localization

    Cell membrane.
  • Information by UniProt

  • Database links

    • Alternative names

      • G protein coupled receptor 14 antibody
      • G-protein coupled receptor 14 antibody
      • GPR14 antibody
      • UR-2-R antibody
      • UR-II-R antibody
      • UR2R_HUMAN antibody
      • Urotensin II receptor (UR II R) antibody
      • Urotensin II receptor antibody
      • Urotensin-2 receptor antibody
      • UTR antibody
      • UTR2 antibody
      • Uts2r antibody
      see all

    Images

    • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR14 antibody - N-terminal (ab150584)
      Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR14 antibody - N-terminal (ab150584)
      Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human pancreas (acinar epithelium) tissue labelling GPCR GPR14 with ab150584 at 11 µg/ml.

    References

    This product has been referenced in:

    • Wu F  et al. Renal Urotensin II System Plays Roles in the Regulation of Blood Pressure in Dahl Salt-Resistant Rat. Int J Hypertens 2016:9146870 (2016). Read more (PubMed: 28097020) »
    • Pang XX  et al. Urotensin II Induces ER Stress and EMT and Increase Extracellular Matrix Production in Renal Tubular Epithelial Cell in Early Diabetic Mice. Kidney Blood Press Res 41:434-49 (2016). Read more (PubMed: 27467277) »
    See all 2 Publications for this product

    Publishing research using ab150584? Please let us know so that we can cite the reference in this datasheet.

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