Anti-GPCR GPR14 antibody - N-terminal (ab150584)
Key features and details
- Rabbit polyclonal to GPCR GPR14 - N-terminal
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GPCR GPR14 antibody - N-terminal
See all GPCR GPR14 primary antibodies -
Description
Rabbit polyclonal to GPCR GPR14 - N-terminal -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Monkey
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Immunogen
A 20 amino acid sythetic peptide from the N terminal extracellular domain of Human GPCR GPR14 (NP_061822.1).
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Positive control
- Human pancreas (acinar epithelium) tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab150584 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P |
Use a concentration of 6 - 11 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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| Notes |
|---|
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IHC-P
Use a concentration of 6 - 11 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. -
Tissue specificity
Most abundant expression in the heart and pancreas. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 2837 Human
- Omim: 600896 Human
- SwissProt: Q9UKP6 Human
- Unigene: 192720 Human
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Alternative names
- G protein coupled receptor 14 antibody
- G-protein coupled receptor 14 antibody
- GPR14 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR14 antibody - N-terminal (ab150584)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human pancreas (acinar epithelium) tissue labelling GPCR GPR14 with ab150584 at 11 µg/ml.
Datasheets and documents
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SDS download
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Datasheet download
References (2)
ab150584 has been referenced in 2 publications.
- Wu F et al. Renal Urotensin II System Plays Roles in the Regulation of Blood Pressure in Dahl Salt-Resistant Rat. Int J Hypertens 2016:9146870 (2016). PubMed: 28097020
- Pang XX et al. Urotensin II Induces ER Stress and EMT and Increase Extracellular Matrix Production in Renal Tubular Epithelial Cell in Early Diabetic Mice. Kidney Blood Press Res 41:434-49 (2016). PubMed: 27467277