Anti-GPCR GPR14 antibody - N-terminal (ab150584)
Key features and details
- Rabbit polyclonal to GPCR GPR14 - N-terminal
- Suitable for: IHC-P
- Reacts with: Rat, Human
- Isotype: IgG
Overview
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Product name
Anti-GPCR GPR14 antibody - N-terminal
See all GPCR GPR14 primary antibodies -
Description
Rabbit polyclonal to GPCR GPR14 - N-terminal -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Rat, Human
Predicted to work with: Monkey
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Immunogen
A 20 amino acid sythetic peptide from the N terminal extracellular domain of Human GPCR GPR14 (NP_061822.1).
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Positive control
- Human pancreas (acinar epithelium) tissue.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab150584 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use a concentration of 6 - 11 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
Target
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Function
High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system. -
Tissue specificity
Most abundant expression in the heart and pancreas. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 2837 Human
- Entrez Gene: 57305 Rat
- Omim: 600896 Human
- SwissProt: Q9UKP6 Human
- SwissProt: P49684 Rat
- Unigene: 192720 Human
- Unigene: 44230 Rat
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Alternative names
- G protein coupled receptor 14 antibody
- G-protein coupled receptor 14 antibody
- GPR14 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR14 antibody - N-terminal (ab150584)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human pancreas (acinar epithelium) tissue labelling GPCR GPR14 with ab150584 at 11 µg/ml.
References (2)
ab150584 has been referenced in 2 publications.
- Wu F et al. Renal Urotensin II System Plays Roles in the Regulation of Blood Pressure in Dahl Salt-Resistant Rat. Int J Hypertens 2016:9146870 (2016). PubMed: 28097020
- Pang XX et al. Urotensin II Induces ER Stress and EMT and Increase Extracellular Matrix Production in Renal Tubular Epithelial Cell in Early Diabetic Mice. Kidney Blood Press Res 41:434-49 (2016). PubMed: 27467277
