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    gpcr-gpr15-antibody-extracellular-domain-ab188938.pdf

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Signal Transduction Signaling Pathway G Protein Signaling GPCR
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Anti-GPCR GPR15 antibody - Extracellular domain (ab188938)

  • Datasheet
  • SDS
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR15 antibody - Extracellular domain (ab188938)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR15 antibody - Extracellular domain (ab188938)

Key features and details

  • Rabbit polyclonal to GPCR GPR15 - Extracellular domain
  • Suitable for: IHC-P
  • Reacts with: Human
  • Isotype: IgG

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Overview

  • Product name

    Anti-GPCR GPR15 antibody - Extracellular domain
    See all GPCR GPR15 primary antibodies
  • Description

    Rabbit polyclonal to GPCR GPR15 - Extracellular domain
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Rabbit, Horse, Cow, Pig, Chimpanzee, Monkey, Gorilla, Common marmoset
  • Immunogen

    Synthetic peptide corresponding to Human GPCR GPR15 (extracellular). The peptide corresponds to 19 amino acids from the 2nd extracellular domain. (NP_005281.1)
    Database link: P49685

  • Positive control

    • Human liver and Human heart tissues.
  • General notes

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

    • Signal Transduction
    • Signaling Pathway
    • G Protein Signaling
    • GPCR

Associated products

  • Compatible Secondaries

    • Goat Anti-Rabbit IgG H&L (Alexa Fluor® 488) (ab150077)
    • Goat Anti-Rabbit IgG H&L (HRP) (ab205718)
  • Isotype control

    • Rabbit IgG, polyclonal - Isotype Control (ChIP Grade) (ab171870)

Applications

Our Abpromise guarantee covers the use of ab188938 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Antigen retrieval requires Proteinase K treatment.

Target

  • Function

    Probable chemokine receptor. Alternative coreceptor with CD4 for HIV-1 infection.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Target information above from: UniProt accession P49685 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links

    • Entrez Gene: 450102 Chimpanzee
    • Entrez Gene: 538740 Cow
    • Entrez Gene: 101129980 Gorilla
    • Entrez Gene: 100072420 Horse
    • Entrez Gene: 2838 Human
    • Entrez Gene: 100153787 Pig
    • Entrez Gene: 100339663 Rabbit
    • Omim: 601166 Human
    • SwissProt: Q9BG77 Chimpanzee
    • SwissProt: P49685 Human
    • Unigene: 563128 Human
    see all
  • Alternative names

    • BOB antibody
    • Brother of Bonzo antibody
    • G protein coupled receptor 15 antibody
    • G protein coupled receptor 15 antibody
    • G protein coupled receptor GPR15 antibody
    • G protein coupled receptor GPR15 antibody
    • G-protein coupled receptor 15 antibody
    • GPR15 antibody
    • GPR15_HUMAN antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR15 antibody - Extracellular domain (ab188938)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR15 antibody - Extracellular domain (ab188938)

    Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue labeling GPCR GPR15 with ab188938 at 10 µg/ml.

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR15 antibody - Extracellular domain (ab188938)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR15 antibody - Extracellular domain (ab188938)

    Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human liver tissue labeling GPCR GPR15 with ab188938 at 10 µg/ml.

Protocols

  • Immunohistochemistry protocols

Click here to view the general protocols

Datasheets and documents

    • Datasheet
    • SDS
  • References (1)

    Publishing research using ab188938? Please let us know so that we can cite the reference in this datasheet.

    ab188938 has been referenced in 1 publication.

    • Pan B  et al. G-protein coupled receptor 15 mediates angiogenesis and cytoprotective function of thrombomodulin. Sci Rep 7:692 (2017). ICC . PubMed: 28386128

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