Anti-GPCR GPR17 antibody - C-terminal (ab136902)
- Datasheet
- References
- Protocols
Overview
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Product name
Anti-GPCR GPR17 antibody - C-terminal
See all GPCR GPR17 primary antibodies -
Description
Goat polyclonal to GPCR GPR17 - C-terminal -
Host species
Goat -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Cow, Human
Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Hamster, Turkey, Pig, Lizard, Monkey, Gorilla, Opossum, Common marmoset, Elephant
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Immunogen
Synthetic peptide:
C-EGKTNESSLSAKSE
, corresponding to C terminal amino acids 353-366 of Human GPCR GPR17 (NP_005282.1). -
Positive control
- Human heart tissue; Human Cerebellum, Mouse and Rat brain lysates.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab136902 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 41 kDa. | |
| IHC-P | Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. -
Tissue specificity
Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 769024 Chicken
- Entrez Gene: 782442 Cow
- Entrez Gene: 101152341 Gorilla
- Entrez Gene: 101843008 Hamster
- Entrez Gene: 2840 Human
- Entrez Gene: 574402 Mouse
- Entrez Gene: 767613 Rat
- Omim: 603071 Human
see all -
Alternative names
- DKFZp686M18273 antibody
- G protein coupled receptor 17 antibody
- G-protein coupled receptor 17 antibody
see all
Images
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR17 antibody - C-terminal (ab136902)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue labelling GPCR GPR17 with ab136902 at 10µg/ml. -
Western blot - Anti-GPCR GPR17 antibody - C-terminal (ab136902)Anti-GPCR GPR17 antibody - C-terminal (ab136902) at 0.1 µg/ml + Human Cerebellum lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 41 kDa
Datasheets and documents
References
ab136902 has not yet been referenced specifically in any publications.
