Anti-GPCR GPR17 antibody - C-terminal (ab136902)
Key features and details
- Goat polyclonal to GPCR GPR17 - C-terminal
- Suitable for: WB, IHC-P
- Reacts with: Cow, Human
- Isotype: IgG
Overview
-
Product name
Anti-GPCR GPR17 antibody - C-terminal
See all GPCR GPR17 primary antibodies -
Description
Goat polyclonal to GPCR GPR17 - C-terminal -
Host species
Goat -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Cow, Human
Predicted to work with: Mouse, Rat, Rabbit, Horse, Chicken, Hamster, Turkey, Pig, Lizard, Monkey, Gorilla, Opossum, Common marmoset, Elephant
-
Immunogen
Synthetic peptide:
C-EGKTNESSLSAKSE
, corresponding to C terminal amino acids 353-366 of Human GPCR GPR17 (NP_005282.1). -
Positive control
- Human heart tissue; Human Cerebellum, Mouse and Rat brain lysates.
-
General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 99% Tris buffered saline, 0.5% BSA -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
Applications
Our Abpromise guarantee covers the use of ab136902 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 41 kDa. | |
| IHC-P | Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
-
Function
Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. -
Tissue specificity
Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
-
Database links
- Entrez Gene: 769024 Chicken
- Entrez Gene: 782442 Cow
- Entrez Gene: 101152341 Gorilla
- Entrez Gene: 101843008 Hamster
- Entrez Gene: 2840 Human
- Entrez Gene: 574402 Mouse
- Entrez Gene: 767613 Rat
- Omim: 603071 Human
see all -
Alternative names
- DKFZp686M18273 antibody
- G protein coupled receptor 17 antibody
- G-protein coupled receptor 17 antibody
see all
Images
-
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR17 antibody - C-terminal (ab136902)Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human heart tissue labelling GPCR GPR17 with ab136902 at 10µg/ml.
-
Western blot - Anti-GPCR GPR17 antibody - C-terminal (ab136902)Anti-GPCR GPR17 antibody - C-terminal (ab136902) at 0.1 µg/ml + Human Cerebellum lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 41 kDa
Protocols
Datasheets and documents
References (0)
ab136902 has not yet been referenced specifically in any publications.
