Anti-GPCR GPR17 antibody - N-terminal (ab150648)
Key features and details
- Rabbit polyclonal to GPCR GPR17 - N-terminal
- Suitable for: IHC-P, ICC
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GPCR GPR17 antibody - N-terminal
See all GPCR GPR17 primary antibodies -
Description
Rabbit polyclonal to GPCR GPR17 - N-terminal -
Host species
Rabbit -
Specificity
BLAST analysis of the peptide immunogen showed no homology with other Human proteins. -
Tested applications
Suitable for: IHC-P, ICCmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Gorilla -
Immunogen
Synthetic peptide corresponding to 16 amino acids from the N-terminal extracellular domain of Human GPCR GPR17 (NP_005282.1).
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Positive control
- Human brain tissue; HEK293 cells transfected with GPCR GPR17.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab150648 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 3 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
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ICC |
Use a concentration of 16 µg/ml.
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Notes |
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IHC-P
Use a concentration of 3 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. |
ICC
Use a concentration of 16 µg/ml. |
Target
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Function
Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. -
Tissue specificity
Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 101152341 Gorilla
- Entrez Gene: 2840 Human
- Omim: 603071 Human
- SwissProt: Q13304 Human
- Unigene: 46453 Human
- Unigene: 688940 Human
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Alternative names
- DKFZp686M18273 antibody
- G protein coupled receptor 17 antibody
- G-protein coupled receptor 17 antibody
see all
Images
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Immunohistochemical analysis of formalin fixed, paraffin embedded Human brain (neurons and glia) tissue, labelling GPCR GPR17 with ab150648 at 1.4 µg/ml.
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Immunocytochemical analysis of HEK293 cells transfected with GPCR GPR17, labelling GPCR GPR17 with ab150648 at 16µg/ml.
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Immunocytochemical analysis of non-transfected HEK293 cells, labelling GPCR GPR17 with ab150648 at 16µg/ml.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab150648 has not yet been referenced specifically in any publications.