Overview

  • Product name

    Anti-GPCR GPR17 antibody - N-terminal
    See all GPCR GPR17 primary antibodies
  • Description

    Rabbit polyclonal to GPCR GPR17 - N-terminal
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-P, ICCmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Gorilla
  • Immunogen

    Synthetic peptide corresponding to 16 amino acids from the N-terminal extracellular domain of Human GPCR GPR17 (NP_005282.1).

  • Positive control

    • Human brain tissue; HEK293 cells transfected with GPCR GPR17.

Properties

Applications

Our Abpromise guarantee covers the use of ab150648 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 3 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC Use a concentration of 16 µg/ml.

Target

  • Function

    Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.
  • Tissue specificity

    Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • DKFZp686M18273 antibody
    • G protein coupled receptor 17 antibody
    • G-protein coupled receptor 17 antibody
    • GPR 17 antibody
    • Gpr17 antibody
    • GPR17_HUMAN antibody
    • P2Y like receptor antibody
    • P2Y-like receptor antibody
    • Probable P2Y purinoceptor GPR 17 antibody
    • Probable P2Y purinoceptor GPR17 antibody
    • R12 antibody
    • UDP/CysLT receptor antibody
    • Uracil nucleotide/cysteinyl leukotriene receptor antibody
    see all

Images

  • Immunohistochemical analysis of formalin fixed, paraffin embedded Human brain (neurons and glia) tissue, labelling GPCR GPR17 with ab150648 at 1.4 µg/ml.
  • Immunocytochemical analysis of HEK293 cells transfected with GPCR GPR17, labelling GPCR GPR17 with ab150648 at 16µg/ml.
  • Immunocytochemical analysis of non-transfected HEK293 cells, labelling GPCR GPR17 with ab150648 at 16µg/ml.

References

ab150648 has not yet been referenced specifically in any publications.

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