Overview

  • Product name

    Anti-GPCR GPR3 antibody - Extracellular domain
    See all GPCR GPR3 primary antibodies
  • Description

    Rabbit polyclonal to GPCR GPR3 - Extracellular domain
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Hamster, Monkey, Gorilla
  • Immunogen

    Synthetic peptide corresponding to Human GPCR GPR3 (extracellular). (15 amino acid peptide from the 2nd extracellular domain).
    Database link: P46089

  • Positive control

    • IHC-P: Human brain (neurons and glia) and ovary carcinoma tissues.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.099% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab219786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 6 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Target

  • Function

    Orphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Has a potential role in modulating a number of brain functions, including behavioral responses to stress (By similarity), amyloid-beta peptide generation in neurons and neurite outgrowth (By similarity). Maintains also meiotic arrest in oocytes.
  • Tissue specificity

    Expressed predominantly in the central nervous system, and at low levels in the lung, kidney, testis, ovary and eye. Highly expressed in regions of the brain implicated in the Alzheimer disease.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • ACCA antibody
    • ACCA orphan receptor antibody
    • Adenylate cyclase constitutive activator antibody
    • G protein coupled receptor 3 antibody
    • G-protein coupled receptor 3 antibody
    • Gpr3 antibody
    • GPR3_HUMAN antibody
    • Probable G protein coupled receptor GPR3 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain, neurons and glia tissue labeling GPCR GPR3 with ab219786 at 6 µg/mL.

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded human ovary carcinoma tissue labeling GPCR GPR3 with ab219786 at 6 µg/mL.

References

ab219786 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab219786.
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