Key features and details
- Rabbit polyclonal to GPCR GPR3 - Extracellular domain
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-GPCR GPR3 antibody - Extracellular domain
See all GPCR GPR3 primary antibodies
DescriptionRabbit polyclonal to GPCR GPR3 - Extracellular domain
SpecificityBLAST analysis of the peptide immunogen showed no homology with other human proteins.
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Hamster, Monkey, Gorilla
Synthetic peptide corresponding to Human GPCR GPR3 (extracellular). (15 amino acid peptide from the 2nd extracellular domain).
Database link: P46089
- IHC-P: Human brain (neurons and glia) and ovary carcinoma tissues.
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We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.099% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab219786 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 6 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
FunctionOrphan receptor with constitutive G(s) signaling activity that activate cyclic AMP. Has a potential role in modulating a number of brain functions, including behavioral responses to stress (By similarity), amyloid-beta peptide generation in neurons and neurite outgrowth (By similarity). Maintains also meiotic arrest in oocytes.
Tissue specificityExpressed predominantly in the central nervous system, and at low levels in the lung, kidney, testis, ovary and eye. Highly expressed in regions of the brain implicated in the Alzheimer disease.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- ACCA antibody
- ACCA orphan receptor antibody
- Adenylate cyclase constitutive activator antibody
ab219786 has not yet been referenced specifically in any publications.