Overview

  • Product name

    Anti-GPCR GPR40 antibody - Cytoplasmic domain
    See all GPCR GPR40 primary antibodies
  • Description

    Rabbit polyclonal to GPCR GPR40 - Cytoplasmic domain
  • Host species

    Rabbit
  • Specificity

    BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Monkey, Gorilla
  • Immunogen

    Synthetic peptide corresponding to Human GPCR GPR40. 19 amino acids from 1st cytoplasmic domain. NP_005294.1.
    Database link: O14842

  • Positive control

    • Human pancreas tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.1% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab188929 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 - 10 µg/ml.

Target

  • Function

    Receptor for medium and long chain saturated and unsaturated fatty acids. Binding of the ligand increase intracellular calcium concentration and amplify glucose-stimulated insulin secretion. The activity of this receptor is mediated by G-proteins that activate phospholipase C. Seems to act through a G(q) and G(i)-mediated pathway.
  • Tissue specificity

    Expressed abundantly in pancreatic beta cells.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • FFA1R antibody
    • FFAR 1 antibody
    • Ffar1 antibody
    • FFAR1_HUMAN antibody
    • Free fatty acid receptor 1 antibody
    • G protein coupled receptor 40 antibody
    • G-protein coupled receptor 40 antibody
    • GPCR40 antibody
    • GPR 40 antibody
    • GPR40 antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human pancreas tissue labeling GPCR GPR40 with ab188929 at 10 µg/ml.

References

ab188929 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab188929.
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