Key features and details
- Rabbit polyclonal to GPCR GPR43
- Suitable for: ELISA, IHC-P, ICC/IF
- Reacts with: Human
- Isotype: IgG
Product nameAnti-GPCR GPR43 antibody
See all GPCR GPR43 primary antibodies
DescriptionRabbit polyclonal to GPCR GPR43
Tested applicationsSuitable for: ELISA, IHC-P, ICC/IFmore details
Species reactivityReacts with: Human
Synthetic peptide conjugated to KLH, corresponding to the C terminal region of Human GPCR GPR43.
- Human tonsil tissue; COS7 cells
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 0.88% Sodium chloride, 50% Glycerol, 49% PBS
PBS is without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab124272 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 µg/ml.|
|ICC/IF||1/100 - 1/500.|
FunctionReceptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate.
Tissue specificityExpressed at relatively high levels in peripheral blood leukocytes and, to lesser, extent, in spleen.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family.
Cellular localizationCell membrane.
- Information by UniProt
- Fatty acid receptor 2 antibody
- FFA2R antibody
- Ffar2 antibody
ab124272 has been referenced in 2 publications.
- Matsuya-Ogawa M et al. Oncoprotective Effects of Short-Chain Fatty Acids on Uterine Cervical Neoplasia. Nutr Cancer 71:312-319 (2019). PubMed: 30836015
- Pan P et al. Loss of free fatty acid receptor 2 enhances colonic adenoma development and reduces the chemopreventive effects of black raspberries in ApcMin/+ mice. Carcinogenesis 38:86-93 (2017). PubMed: 27866157