Overview

  • Product name

    Anti-GPCR GPR48/LGR4 antibody
    See all GPCR GPR48/LGR4 primary antibodies
  • Description

    Rabbit polyclonal to GPCR GPR48/LGR4
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human GPCR GPR48/LGR4 aa 759-852.
    Database link: Q9BXB1

  • Positive control

    • A431, H1299, HeLa and Raji whole lysates; Human HSC3 xenograft tissue.
  • General notes

    Keep as concentrated solution.

     This product was previously labelled as GPCR GPR48

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: PBS, 50% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab137480 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 104 kDa.
IHC-P 1/100 - 1/1000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Orphan receptor.
  • Tissue specificity

    Expressed in multiple steroidogenic tissues: placenta, ovary, testis and adrenal. Expressed also in spinal cord, thyroid, stomach, trachea, heart, pancreas, kidney, prostate and spleen.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
    Contains 15 LRR (leucine-rich) repeats.
    Contains 1 LRRNT domain.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • BNMD17 antibody
    • G protein coupled receptor 48 antibody
    • G-protein coupled receptor 48 antibody
    • GPR48 antibody
    • Leucine-rich repeat-containing G protein-coupled receptor 4 antibody
    • Leucine-rich repeat-containing G-protein coupled receptor 4 antibody
    • LGR4 antibody
    • LGR4_HUMAN antibody
    see all

Images

  • Anti-GPCR GPR48/LGR4 antibody (ab137480) at 1/1000 dilution + HeLa whole cell lysate at 30 µg

    Predicted band size: 104 kDa



    7.5% SDS PAGE
  • Immunohistochemical analysis of paraffin embedded Human HSC3 xenograft tissue, labelling GPCR GPR48/LGR4 with ab137480 at 1/250 dilution.

References

This product has been referenced in:

  • Nikitakis NG  et al. DSPP-MMP20 gene silencing downregulates cancer stem cell markers in human oral cancer cells. Cell Mol Biol Lett 23:30 (2018). Read more (PubMed: 30002682) »
  • Shi GX  et al. Evidence of the Role of R-Spondin 1 and Its Receptor Lgr4 in the Transmission of Mechanical Stimuli to Biological Signals for Bone Formation. Int J Mol Sci 18:N/A (2017). WB ; Mouse . Read more (PubMed: 28272338) »
See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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