Anti-GPCR GPR48/LGR4 antibody (ab140845)
Key features and details
- Rabbit polyclonal to GPCR GPR48/LGR4
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-GPCR GPR48/LGR4 antibody
See all GPCR GPR48/LGR4 primary antibodies -
Description
Rabbit polyclonal to GPCR GPR48/LGR4 -
Host species
Rabbit -
Tested applications
Suitable for: IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat, Rabbit, Chicken, Cow, Pig, Monkey, Common marmoset, Elephant -
Immunogen
Synthetic peptide corresponding to Human GPCR GPR48/LGR4 (N terminal).
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Positive control
- Human brain, caudate, tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C. Store undiluted. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: 99% PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab140845 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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IHC-P |
Use a concentration of 4 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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Notes |
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IHC-P
Use a concentration of 4 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
Target
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Function
Orphan receptor. -
Tissue specificity
Expressed in multiple steroidogenic tissues: placenta, ovary, testis and adrenal. Expressed also in spinal cord, thyroid, stomach, trachea, heart, pancreas, kidney, prostate and spleen. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family.
Contains 15 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 55366 Human
- Entrez Gene: 107515 Mouse
- Entrez Gene: 286994 Rat
- Omim: 606666 Human
- SwissProt: Q9BXB1 Human
- SwissProt: A2ARI4 Mouse
- SwissProt: Q9Z2H4 Rat
- Unigene: 502176 Human
see all -
Alternative names
- BNMD17 antibody
- G protein coupled receptor 48 antibody
- G-protein coupled receptor 48 antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab140845 has been referenced in 1 publication.
- Luo W et al. Leucine-rich repeat-containing G protein-coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial-mesenchymal transition. J Biol Chem 292:15525-15537 (2017). PubMed: 28768769