• Product name

  • Description

    Goat polyclonal to GPCR GPR81
  • Host species

  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Dog, Pig
  • Immunogen

    Synthetic peptide:


    , corresponding to internal sequence amino acids 207-220 of Human GPCR GPR81 (NP_115943.1).

  • Positive control

    • Human liver lysate


  • Form

  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • Clonality

  • Isotype

  • Research areas


Our Abpromise guarantee covers the use of ab106942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 40, 55 kDa (predicted molecular weight: 39 kDa).


  • Function

    Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway.
  • Tissue specificity

    Expressed abundantly in brown and white fat. It also detectable at lower levels in liver, kidney, skeletal muscle, brain and pituitary. Not detected in frontal, temporal and occipital lobes of the cortex, basal forebrain, caudate nucleus, nucleus accumbens and hippocampus.
  • Sequence similarities

    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Form

    G protein-coupled receptors (GPCRs, or GPRs), such as GPR81, contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins.
  • Alternative names

    • FKSG80 antibody
    • FKSG80 protein antibody
    • G protein coupled receptor 104 antibody
    • G protein coupled receptor 81 antibody
    • G protein coupled receptor GPR81 antibody
    • G-protein coupled receptor 104 antibody
    • G-protein coupled receptor 81 antibody
    • GPR 104 antibody
    • GPR 81 antibody
    • GPR104 antibody
    • GPR81 antibody
    • GPR81_HUMAN antibody
    • HCA1 antibody
    • HCAR1 antibody
    • hydroxy-carboxylic acid receptor 1 antibody
    • Hydroxycarboxylic acid receptor 1 antibody
    • LACR1 antibody
    • lactate receptor 1 antibody
    • Putative chemokine receptor antibody
    • T cell activation G protein coupled receptor antibody
    • TA GPCR antibody
    see all


  • Anti-GPCR GPR81 antibody (ab106942) at 0.5 µg/ml + Human liver lysate at 35 µg

    Developed using the ECL technique.

    Predicted band size: 39 kDa
    Observed band size: 40 kDa
    why is the actual band size different from the predicted?
    Additional bands at: 55 kDa. We are unsure as to the identity of these extra bands.

    Exposure time: 1 hour

    An additional band of unknown identity was also consistently observed at 55 kDa. This band was successfully blocked by incubation with the immunizing peptide.


This product has been referenced in:

  • Wagner W  et al. L- and D-lactate enhance DNA repair and modulate the resistance of cervical carcinoma cells to anticancer drugs via histone deacetylase inhibition and hydroxycarboxylic acid receptor 1 activation. Cell Commun Signal 13:36 (2015). WB ; Human . Read more (PubMed: 26208712) »
See 1 Publication for this product

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