Overview

  • Product name
    Anti-GPCR MRGX2 antibody [1D3]
    See all GPCR MRGX2 primary antibodies
  • Description
    Mouse monoclonal [1D3] to GPCR MRGX2
  • Host species
    Mouse
  • Tested applications
    Suitable for: Flow Cyt, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    DNA vaccine.

  • Positive control
    • Human placenta and pancreas tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab167125 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

ab170192 - Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

 

IHC-P Use a concentration of 1 µg/ml. Pretreatment with proteinase K required

Target

  • Function
    Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.
  • Tissue specificity
    Has a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • G protein coupled receptor MRGX 2 antibody
    • G protein coupled receptor MRGX2 antibody
    • Mas related G protein coupled receptor member X2 antibody
    • Mas related gene MRGX 2 antibody
    • Mas related gene MRGX2 antibody
    • MAS related GPR member X2 antibody
    • Mas-related G-protein coupled receptor member X antibody
    • Mas-related G-protein coupled receptor member X2 antibody
    • MRGPRX 2 antibody
    • MRGPRX2 antibody
    • MRGX 2 antibody
    • MRGX2 antibody
    • MRGX2_HUMAN antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human pancreas tissue labeling GPCR MRGX2 using ab167125 at 1 µg/ml dilution.

References

ab167125 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab167125.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

Sign up