Key features and details
- Mouse monoclonal [1D3] to GPCR MRGX2
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG2b
Product nameAnti-GPCR MRGX2 antibody [1D3]
See all GPCR MRGX2 primary antibodies
DescriptionMouse monoclonal [1D3] to GPCR MRGX2
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
- Human placenta and pancreas tissues.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.20
Preservative: 0.1% KATHON™ CG/ICP
Constituents: 99% PBS, 0.5% BSA
Concentration information loading...
PurityProtein G purified
Purification notesAffinity purified from serum-free cell culture supernatant
Light chain typekappa
Our Abpromise guarantee covers the use of ab167125 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 1 µg/ml. Pretreatment with proteinase K required|
FunctionOrphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Cortistatin-14 seems to be a high potency ligand at this receptor. Cortistatin has several biological functions including roles in sleep regulation locomotor activity, and cortical function. In receptor-expressing cells, cortistatin-stimulated increases in intracellular Ca(2+) but had no effect on basal or forskolin-stimulated cAMP levels, suggesting that this receptor is G(q)-coupled.
Tissue specificityHas a limited expression profile, both peripheral and within the central nervous system, with highest levels in dorsal root ganglion.
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. Mas subfamily.
Cellular localizationCell membrane.
- Information by UniProt
- G protein coupled receptor MRGX 2 antibody
- G protein coupled receptor MRGX2 antibody
- Mas related G protein coupled receptor member X2 antibody
ab167125 has not yet been referenced specifically in any publications.