Overview

  • Product name
    Anti-GPCR RDC1/CXCR-7 antibody
    See all GPCR RDC1/CXCR-7 primary antibodies
  • Description
    Rabbit polyclonal to GPCR RDC1/CXCR-7
  • Host species
    Rabbit
  • Specificity
    ab113410 detects endogenous levels of total GPCR RDC1/CXCR-7 protein.
  • Tested applications
    Suitable for: WB, ELISA, IHC-P, ICC/IFmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Human GPCR RDC1/CXCR-7 (C terminal) conjugated to keyhole limpet haemocyanin.

  • Positive control
    • Human Brain cortex and cerebellum tissues; COS7 cell extract; COS7 cells.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol
    Note: PBS (without Mg2+, Ca2+)
  • Concentration information loading...
  • Purity
    Protein A purified
  • Clonality
    Polyclonal
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab113410 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 41 kDa.
ELISA 1/1000.
IHC-P Use a concentration of 10 µg/ml.
ICC/IF 1/100 - 1/500.

Target

  • Function
    Receptor for CXCL12/SDF1. Acts as coreceptor with CXCR4 for a restricted number of HIV isolates.
  • Tissue specificity
    Expressed in monocytes, basophils, and B-cells. Lower expression in CD4+ T-lymphocytes and natural killer cells.
  • Sequence similarities
    Belongs to the G-protein coupled receptor 1 family.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • ACKR3 antibody
    • atypical chemokine receptor 3 antibody
    • C X C chemokine receptor type 7 antibody
    • C-X-C chemokine receptor type 7 antibody
    • Chemokine (C-X-C motif) receptor 7 antibody
    • Chemokine C X C motif receptor 7 antibody
    • Chemokine orphan receptor 1 antibody
    • CMKOR1 antibody
    • CXC R7 antibody
    • CXC-R7 antibody
    • CXCR 7 antibody
    • CXCR-7 antibody
    • CXCR7 antibody
    • CXCR7_HUMAN antibody
    • G protein coupled receptor 159 antibody
    • G protein coupled receptor antibody
    • G protein coupled receptor RDC1 homolog antibody
    • G-protein coupled receptor 159 antibody
    • G-protein coupled receptor RDC1 homolog antibody
    • GPCR RDC1 antibody
    • GPR159 antibody
    • GPRN1 antibody
    • RDC 1 antibody
    • RDC-1 antibody
    • RDC1 antibody
    see all

Images

  • ab113410 at 10 &microg/ml staining GPCR RDC1/CXCR-7 in Human Brain cortex by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

  • ab113410 at 10 µg/ml staining GPCR RDC1/CXCR-7 in Human Brain cerebellum by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

  • All lanes : Anti-GPCR RDC1/CXCR-7 antibody (ab113410) at 1/500 dilution

    Lane 1 : COS7 cell extract
    Lane 2 : COS7 cell extract with synthesized peptide

    Predicted band size: 41 kDa

  • Immunofluorescence analysis of COS7 cells, using ab113410 at 1/100 dilution. The image on the right is treated with the synthesized peptide.

References

ab113410 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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