Key features and details
- Rabbit polyclonal to GPCR TGR7 - Cytoplasmic domain
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-GPCR TGR7 antibody - Cytoplasmic domain
See all GPCR TGR7 primary antibodies
DescriptionRabbit polyclonal to GPCR TGR7 - Cytoplasmic domain
SpecificityBLAST analysis of the peptide immunogen showed no homology with other Human proteins.
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Gorilla
Synthetic peptide within Human GPCR TGR7. The exact sequence is proprietary. The peptide corresponds to 18 amino acids from the 4th cytoplasmic domain. (NP_944605.2)
Database link: Q8TDS7
- Human brain, medulla, tissue
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.1% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab189006 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
FunctionMay regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. Mas subfamily.
Cellular localizationCell membrane. Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
- Information by UniProt
- Beta alanine receptor antibody
- Beta-alanine receptor antibody
- G protein coupled receptor TGR7 antibody
ab189006 has not yet been referenced specifically in any publications.