RecombinantRabMAb

Recombinant Anti-GPCR TGR7 antibody [EPR10597] (ab155099)

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Key features and details

  • Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
  • Rabbit monoclonal [EPR10597] to GPCR TGR7
  • Suitable for: WB
  • Reacts with: Mouse, Rat, Human

Overview

  • Product name

    Anti-GPCR TGR7 antibody [EPR10597]
    See all GPCR TGR7 primary antibodies

  • Description

    Rabbit monoclonal [EPR10597] to GPCR TGR7

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP

  • Species reactivity

    Reacts with: Mouse, Rat, Human

  • Immunogen

    Synthetic peptide, corresponding to residues in Human GPCR TGR7 (UniProt: Q8TDS7).

  • Positive control

    • Human testis, bladder, muscle and fetal heart lysates.

  • General notes

     

     

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

    Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

    Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

    We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

    In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

    We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

    Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

    Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

Properties

Applications

Our Abpromise guarantee covers the use of ab155099 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 36 kDa.
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.

    • Target

    • Function

      May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).

    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family. Mas subfamily.

    • Cellular localization

      Cell membrane. Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
    • Information by UniProt

    • Database links

      see all

    • Alternative names

      • Beta alanine receptor antibody
      • Beta-alanine receptor antibody
      • G protein coupled receptor TGR7 antibody
      • G-protein coupled receptor TGR7 antibody
      • mas related G protein coupled MRGD antibody
      • Mas related G protein coupled receptor member D antibody
      • MAS related GPR member D antibody
      • Mas-related G-protein coupled receptor member D antibody
      • MRGD antibody
      • Mrgprd antibody
      • MRGRD_HUMAN antibody
      • TGR7 antibody
      see all

    Images

    • Western blot - Anti-GPCR TGR7 antibody [EPR10597] (ab155099)
      Western blot - Anti-GPCR TGR7 antibody [EPR10597] (ab155099)
      All lanes : Anti-GPCR TGR7 antibody [EPR10597] (ab155099) at 1/1000 dilution

      Lane 1 : Human testis lysate
      Lane 2 : Human bladder lysate
      Lane 3 : Human muscle lysate
      Lane 4 : Human fetal heart lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-rabbit HRP at 1/2000 dilution

      Predicted band size: 36 kDa

    • Anti-GPCR TGR7 antibody [EPR10597] (ab155099)
      Anti-GPCR TGR7 antibody [EPR10597] (ab155099)

    References (1)

    Publishing research using ab155099? Please let us know so that we can cite the reference in this datasheet.

    ab155099 has been referenced in 1 publication.

    • Zhou C  et al. Expression and localization of MrgprD in mouse intestinal tract. Cell Tissue Res N/A:N/A (2019). PubMed: 30919047

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