Product nameAnti-GPCR TGR7 antibody [EPR10597]
See all GPCR TGR7 primary antibodies
DescriptionRabbit monoclonal [EPR10597] to GPCR TGR7
Tested applicationsSuitable for: WBmore details
Unsuitable for: ICC,IHC-P or IP
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide, corresponding to residues in Human GPCR TGR7 (UniProt: Q8TDS7).
- Human testis, bladder, muscle and fetal heart lysates.
Storage instructionsShipped at 4°C. Store at -20ºC.
Storage bufferPreservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
PurityTissue culture supernatant
Immunizing Peptide (Blocking)
Our Abpromise guarantee covers the use of ab155099 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000 - 1/10000. Predicted molecular weight: 36 kDa.Can be blocked with GPCR TGR7 peptide (ab218717).|
FunctionMay regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. Mas subfamily.
Cellular localizationCell membrane. Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
- Information by UniProt
- Beta alanine receptor antibody
- Beta-alanine receptor antibody
- G protein coupled receptor TGR7 antibody
All lanes : Anti-GPCR TGR7 antibody [EPR10597] (ab155099) at 1/1000 dilution
Lane 1 : Human testis lysate
Lane 2 : Human bladder lysate
Lane 3 : Human muscle lysate
Lane 4 : Human fetal heart lysate
Lysates/proteins at 10 µg per lane.
All lanes : Goat anti-rabbit HRP at 1/2000 dilution
Predicted band size: 36 kDa
ab155099 has not yet been referenced specifically in any publications.