Recombinant
RabMAb

Recombinant Anti-GPCR TGR7 antibody [EPR10597] - BSA and Azide free (ab240132)

Overview

  • Product name

    Anti-GPCR TGR7 antibody [EPR10597] - BSA and Azide free
    See all GPCR TGR7 primary antibodies
  • Description

    Rabbit monoclonal [EPR10597] to GPCR TGR7 - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human GPCR TGR7. The exact sequence is proprietary.

  • General notes

    Ab240132 is the carrier-free version of ab155099. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    ab240132 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab240132 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 36 kDa.Can be blocked with GPCR TGR7 peptide (ab218717).
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Function

      May regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
    • Sequence similarities

      Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
    • Cellular localization

      Cell membrane. Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
    • Information by UniProt
    • Database links

    • Alternative names

      • Beta alanine receptor antibody
      • Beta-alanine receptor antibody
      • G protein coupled receptor TGR7 antibody
      • G-protein coupled receptor TGR7 antibody
      • mas related G protein coupled MRGD antibody
      • Mas related G protein coupled receptor member D antibody
      • MAS related GPR member D antibody
      • Mas-related G-protein coupled receptor member D antibody
      • MRGD antibody
      • Mrgprd antibody
      • MRGRD_HUMAN antibody
      • TGR7 antibody
      see all

    References

    ab240132 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab240132.
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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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