Product nameGPCR TGR7 peptide
See all GPCR TGR7 proteins and peptides
Purity> 90 % n/a.
Our Abpromise guarantee covers the use of ab218717 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-GPCR TGR7 antibody [EPR10597] (ab155099)
- First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
- If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
- Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
- Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
- Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.
Concentration information loading...
Preparation and Storage
Stability and Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
- Beta alanine receptor
- Beta-alanine receptor
- G protein coupled receptor TGR7
FunctionMay regulate nociceptor function and/or development, including the sensation or modulation of pain. Functions as a specific membrane receptor for beta-alanine. Beta-alanine at micromolar doses specifically evoked Ca(2+) influx in cells expressing the receptor. Beta-alanine decreases forskolin-stimulated cAMP production in cells expressing the receptor, suggesting that the receptor couples with G-protein G(q) and G(i).
Sequence similaritiesBelongs to the G-protein coupled receptor 1 family. Mas subfamily.
Cellular localizationCell membrane. Localized at the plasma membrane but internalized into the cytoplasm after treatment with beta-alanine.
- Information by UniProt
ab218717 has not yet been referenced specifically in any publications.