Key features and details
- Nonhydrolyzable GTP analog
- CAS Number: 10470-57-2
- Purity: > 95%
- Soluble in water to 75 mM
- Form / State: Solid
- Source: Synthetic
Product nameGppCp (GMPPCP), Nonhydrolyzable GTP analog
DescriptionNonhydrolyzable GTP analog
Biological descriptionNonhydrolyzable GTP analog. Modulates G-protein cell signaling, protein synthesis and other metabolic processes. Forms stable protein complexes.
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in water to 75 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab146660 has been referenced in 2 publications.
- Wandel MP et al. Guanylate-binding proteins convert cytosolic bacteria into caspase-4 signaling platforms. Nat Immunol 21:880-891 (2020). PubMed: 32541830
- Kumar S et al. Mechanism of Stx17 recruitment to autophagosomes via IRGM and mammalian Atg8 proteins. J Cell Biol 217:997-1013 (2018). PubMed: 29420192