Overview

  • Product name

  • Description

    Rabbit polyclonal to GPR172B
  • Host species

    Rabbit
  • Specificity

    The antibody detects endogenous levels of total GPR172B protein.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human GPR172B (internal sequence).
    Database link: Q9NWF4

  • Positive control

    • Human thyroid cancer tissue and human gastric cancer tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab198825 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Riboflavin transporter. Riboflavin transport is Na(+)-independent but moderately pH-sensitive. Activity is strongly inhibited by riboflavin analogs, such as lumiflavin. Weakly inhibited by flavin adenine dinucleotide (FAD). In case of infection by retroviruses, acts as a cell receptor to retroviral envelopes similar to the porcine endogenous retrovirus (PERV-A).
  • Tissue specificity

    Widely expressed. Highly expressed in the testis, placenta and small intestine. Expressed at lower level in other tissues.
  • Involvement in disease

    Riboflavin deficiency
  • Sequence similarities

    Belongs to the riboflavin transporter family.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • FLJ10060 antibody
    • G protein coupled receptor 172B antibody
    • GPCR antibody
    • GPCR42 antibody
    • hRFT1 antibody
    • member 1 antibody
    • OTTHUMP00000125300 antibody
    • PAR2 antibody
    • PERV-A receptor 2 antibody
    • PERVA receptor 2 antibody
    • Porcine endogenous retrovirus A receptor 2 antibody
    • Protein GPR172B antibody
    • Putative G protein coupled receptor GPCR42 antibody
    • Riboflavin transporter 1 antibody
    • riboflavin transporter antibody
    • S52A1_HUMAN antibody
    • SLC52A1 antibody
    • Solute carrier family 52 antibody
    • Solute carrier family 52, riboflavin transporter, member 1 antibody
    see all

Images

  • Immunohistochemical staining of paraffin-embedded human gastric cancer tissue labeling GPR172B using ab198825 at a 1/40 dilution.

  • Immunohistochemical staining of Human thyroid cancer tissue labeling GPR172B using ab198825 at 1/40 dilution.

References

ab198825 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab198825.
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